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Loxoprofen
go.drugbank.com/drugs/DB09212ApprovedInvestigationalA transdermal preparation was approved for use in Japan in January 2006. … It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina.
Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical UseMotixafortide
go.drugbank.com/drugs/DB14939ApprovedInvestigational[A261476] Motixafortide was approved by the FDA in September 2023, in combination with filgrastim, for use in stem cell mobilization prior to autologous stem cell transplant in patients with multiple … [L48141] It has also been investigated alongside [pembrolizumab] for the treatment of pancreatic cancer.[A261481]
Alanine
go.drugbank.com/drugs/DB00160ApprovedInvestigationalNutraceuticalIt is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
Mixtures: GLAMIN SOLUTION FOR INFUSION, KABIVEN EMULSION FOR INFUSIONMirvetuximab soravtansine
go.drugbank.com/drugs/DB12489ApprovedInvestigational[L50306] In October 2024, it was approved in the EU for the same indication. [L52640] … linker to the genotoxic compound DM4 (also known as soravtansine or ravtansine).
Ioxitalamic acid
go.drugbank.com/drugs/DB13444ApprovedWithdrawn[A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. … [A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg.
Categories: Compounds used in a research, industrial, or household settingAltretamine
go.drugbank.com/drugs/DB00488ApprovedWithdrawnIt also acts as a chemosterilant for male houseflies and other insects.
Allogeneic processed thymus tissue
go.drugbank.com/drugs/DB16736Approved[L38929] Congenital athymia is a rare condition that leads to the absence of a thymus at birth and a high premature mortality rate, with patients typically dying by age two or three. … Allogeneic processed thymus tissue implantation works by migrating the recipient’s bone marrow-derived stem cells to the implanted cultured thymus tissue that develops immunocompetent naïve T cells.
Lincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approved[A190621] Clinical use of lincomycin has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains … [A190657, A190621] Lincomycin was approved by the FDA on December 29, 1964.[L33214]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: UTO LINCOMYCINIsocarboxazid
go.drugbank.com/drugs/DB01247Approved[T115] It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Antidepressive Agents Indicated for DepressionConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigationalBoth of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble. … However, until 1986 official clinical trials were performed and this product was determined to be effective for the treatment of osteoporosis.