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Fruquintinib
go.drugbank.com/drugs/DB11679ApprovedInvestigationalof off-target toxicity. … Therefore, the advent of fruquintinib, a new generation of VEGFR inhibitors with a high kinome selectivity, demonstrated the feasibility of the small-molecule inhibitor approach.
Lecanemab
go.drugbank.com/drugs/DB14580ApprovedInvestigationalof Alzheimer’s disease. … [A253962,L44547] On January 6, 2023, lecanemab was granted accelerated approval by the FDA for the treatment of Alzheimer’s Disease.[L44547] It was granted full FDA approval on July 6, 2023.
Gefitinib
go.drugbank.com/drugs/DB00317ApprovedInvestigationalGefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer.
Products: GEFITINIB EG, GEFTRA® 250 MGYellow fever vaccine
go.drugbank.com/drugs/DB10805ApprovedInvestigationalof the yellow fever vaccine virus. … Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a _flavivirus_ through the bite of an infected mosquito.
Ziftomenib
go.drugbank.com/drugs/DB17171ApprovedInvestigational[A274738] This drug was approved by the FDA on November 13th, 2025, for the treatment of relapsed or refractory acute myeloid leukemia (AML) in adults with a susceptible NPM1 mutation who have no satisfactory … [L54601] Ziftomenib works by preventing the protein-protein interaction between menin and KMT2A, a complex essential for maintaining the proliferation and survival of these leukemic cells.
Calcium glycerophosphate
go.drugbank.com/drugs/DB11264ApprovedBy FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings … It is also present in dental or oral hygiene products due to its cariostatic effects.
Oxymetholone
go.drugbank.com/drugs/DB06412ApprovedIllicitThe uncontrolled misuse of oxymetholone can lead to a large variety of detrimental effects, the most often reported of which are cardiovascular events. … in malnourished or underdeveloped patients.
Products: ANAPOLON 50 MG TABLET, 30 ADET, ANAPOLON 50 MG TABLET, 90 ADETZavegepant
go.drugbank.com/drugs/DB15688ApprovedInvestigationalof oral zavegepant (150 mg bid) in subjects with mild allergic asthma. … [A258190,A258195] In March 2023, the FDA approved the use of zavegepant nasal spray for the acute treatment of migraine with or without aura in adults.
Loncastuximab tesirine
go.drugbank.com/drugs/DB16222ApprovedInvestigationalZylonta also received approval in the EU on December 22, 2022. … [L45206] This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial.
Mezlocillin
go.drugbank.com/drugs/DB00948ApprovedSemisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Categories: combinations of penicillins, Penicillin G