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Colistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalColistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally. … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes.
Cannabidivarin
go.drugbank.com/drugs/DB14050InvestigationalCompared to its homolog, [DB09061], CBDV is shortened by two methyl (CH2) groups on its side chain. … The anti-epileptic activity of CBD and CBDV is thought to be modulated by their effects on transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor
Lacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigationalLacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008.
Synonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDEPoa compressa pollen
go.drugbank.com/drugs/DB10713ApprovedPoa compressa pollen is the pollen of the Poa compressa plant. Poa compressa pollen is mainly used in allergenic testing.
Mixtures: Mixture of Standardized and Non-Standardized Inland Grasses, Mixture of Twenty-Two Standardized and Non-Standardized GrassesCategories: Non-Standardized Pollen Allergenic ExtractNevirapine
go.drugbank.com/drugs/DB00238ApprovedInvestigationalStructurally, nevirapine belongs to the dipyridodiazepinone chemical class. … A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS.
Mixtures: ZIMODINE N ®, LAVUZID® NCategories: Non-Nucleoside Reverse Transcriptase Inhibitors, Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase InhibitorFinafloxacin
go.drugbank.com/drugs/DB09047ApprovedWithdrawnFinafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014. … Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.
Boceprevir
go.drugbank.com/drugs/DB08873ApprovedWithdrawnVictrelis is no longer widely used as interferon-free therapies have been developed. … Boceprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV).
Tegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawn[L5918,F4229] Zelnorm (tegaserod) by Sloan Pharma subsequently gained re-approval in April of 2019.[L5918] Nevertheless, tegaserod remains un-approved in certain regions. … cardiovascular risk have resulted in the limited reintroduction or 're-approval' of tegaserod for treatment of IBS-C specifically in female patients less than 65 years of age and whom are considered to
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMannitol
go.drugbank.com/drugs/DB00742ApprovedInvestigationalOn October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for … this indication under the name BRONCHITOL® by Chiesi USA Inc.
Trimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalTrimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries. … It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form.
International brands: Ni Wei Fu, Procinet NF