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Golodirsen
go.drugbank.com/drugs/DB15593ApprovedInvestigationalOften, patients succumb to this condition by age 30 or younger due to cardiac and respiratory complications. … [L10755,L10758] Golodirsen was initially rejected for FDA approval over concerns about its potential renal toxicity, however, clinical trials did not show significant toxicity.[L10755]
International brands: Vyondys 53Products: Vyondys 53JZP-386 free base
go.drugbank.com/drugs/DB17068ExperimentalJZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.
Synonyms: JZP-386 free baseBretylium
go.drugbank.com/drugs/DB01158ApprovedRecent evidence has shown that bretylium may also inhibit the Na,K-ATPase by binding to the extracellular K-site.
Mixtures: Bretylium Tosylate 0.4% and Dextrose 5% Inj, Bretylium Tosylate 0.2% and Dextrose 5% InjProducts: Bretylate Inj 50mg/ml, Bretylium Tosylate Inj 50mg/mlSiponimod
go.drugbank.com/drugs/DB12371ApprovedInvestigationalSiponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). … It was approved by the FDA on March 26, 2019 [L5792] and by Health Canada on February 20, 2020.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: MAYZENT FILM-COATED TABLET 2MGPhosphoric acid
go.drugbank.com/drugs/DB09394ApprovedInvestigationalPhosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.
Mixtures: HEPATAMINE %8 500 ML(SETLI), HEPATAMINE %8 500 ML(SETSIZ)Tozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigationalComirnaty is also approved for use as a fourth booster shot in adults 50 years of age and older.[L41350] … [L26996] Full FDA approval was granted on August 23, 2021.
Mixtures: Comirnaty Original & Omicron Ba.4/ba.5, Comirnaty Original & Omicron Ba.4/ba.5Products: Comirnaty Omicron XBB.1.5 10 micrograms/dose Dispersion for Injection, Comirnaty Omicron XBB.1.5 30 micrograms/dose Dispersion for InjectionOpiranserin
go.drugbank.com/drugs/DB16271InvestigationalOpiranserin is under investigation in clinical trial NCT03997838 (Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-operative Pain Following Abdominoplasty).
Synonyms: Vvz-149 free baseCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsRevaprazan
go.drugbank.com/drugs/DB16308InvestigationalRevaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(nerd)).
Synonyms: Yh-1885 free base