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Ridaforolimus
go.drugbank.com/drugs/DB06233InvestigationalCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsMaribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigationalMaribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation. … DNA polymerase-based therapies, and their use is often limited by toxicities like myelosuppression and renal injury.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: Livtencity 200 mg Film Kaplı Tablet (112 (56'lık 2 şişe) Adet)Eflornithine
go.drugbank.com/drugs/DB06243ApprovedInvestigationalWithdrawnEflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. … [A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or interacts with ras, both very well-known oncogenes, thus increasing the interest in targeting ornithine carboxylase as a
Synonyms: (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid, 2-(difluoromethyl)ornithineFluasterone
go.drugbank.com/drugs/DB06250ExperimentalHas antiproliferative effects on HIV-1 and reduces HIV-1 replication.
Thioctic acid tromethamine
go.drugbank.com/drugs/DB06253ExperimentalA salt of alpha-lipoic acid and tromethamine; may be useful in treating vascular stress in patients with diabetes.
Synonyms: (R)-5-(1,2-dithiolaln-3-yl)-pentanoic acid tromethaminerPSGL-Ig
go.drugbank.com/drugs/DB06256InvestigationalRecombinant P-selectin glycoprotein ligand IgG fusion protein (rPSGL-Ig) is a fusion protein of human P-selectin ligand and IgG1-Fc.
Synonyms: rPSGL-1-Ig, Recombinant soluble PSGL-1 Fc chimeraLonidamine
go.drugbank.com/drugs/DB06266InvestigationalLonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). … In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acidMAHDL01
go.drugbank.com/drugs/DB06270ExperimentalMAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.