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TAS-106
go.drugbank.com/drugs/DB06656InvestigationalTAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours [A31693].
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-Amino-1-((2R,3R,4R,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one, 3'-C-EthynylcytidineANC-501
go.drugbank.com/drugs/DB18907InvestigationalANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(3-Chlorophenyl)-1,5-dihydro-N-(1-methylethyl)-1-[4-[2-(4-morpholinyl)ethyl]phenyl]-5-oxo-4H-1,2,4-triazole-4-acetamideL-lysyl-l-arginine
go.drugbank.com/drugs/DB19436InvestigationalL-lysyl-l-arginine is under investigation in clinical trial NCT03972488 (Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET).
Synonyms: (2s)-2-(((2s)-2,6-bis(azanyl)hexanoyl)amino)-5-carbamimidamido-pentanoic acid, L-lysyl-l-arginineLuvixasertib
go.drugbank.com/drugs/DB19200InvestigationalLuvixasertib is under investigation in clinical trial NCT05251714 (CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer).
Categories: Heterocyclic Compounds, 1-RingSynonyms: Benzamide, n-cyclopropyl-4-(7-(((cis-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(3-pyridinyloxy)pyrazolo(1,5-a)pyrimidin-3-yl)-2-methyl-, N-cyclopropyl-4-(7-(((cis-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(3-pyridinyloxy)pyrazolo(1,5-a)pyrimidin-3-yl)-2-methylbenzamideAtuliflapon
go.drugbank.com/drugs/DB19029InvestigationalAtuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-severe Uncontrolled Asthma).
Categories: Heterocyclic Compounds, 1-RingSynonyms: (1r,2r)-2-(4-(3-methyl-1h-pyrazol-5-yl)benzoyl)-n-(4-oxo-6,7-dihydro-5h-pyrazolo(1,5-a)pyrazine-3-yl)cyclohexanecarboxamide, Cyclohexanecarboxamide, 2-(4-(5-methyl-1h-pyrazol-3-yl)benzoyl)-n-(4,5,6,7-tetrahydro-4-oxopyrazolo(1,5-a)pyrazin-3-yl)-, (1r,2r)-{4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid
go.drugbank.com/drugs/DB04285ExperimentalSynonyms: {4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID
go.drugbank.com/drugs/DB08131ExperimentalSynonyms: 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACIDTamatinib
go.drugbank.com/drugs/DB07159InvestigationalSynonyms: 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
go.drugbank.com/drugs/DB08553Experimental(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime is a solid. This compound belongs to the phenylpyrazoles. … These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group. It targets the protein serine/threonine-protein kinase B-raf.
Synonyms: (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oximePF-4136309
go.drugbank.com/drugs/DB17200InvestigationalSynonyms: Benzamide, n-(2-((3s)-3-((trans-4-hydroxy-4-(5-(2-pyrimidinyl)- 2-pyridinyl)cyclohexyl)amino)-1-pyrrolidinyl)-2-oxoethyl)-3-(trifluoromethyl)-, N-(2-((3s)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2- yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamideCategories: Heterocyclic Compounds, 1-Ring