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Ampreloxetine
go.drugbank.com/drugs/DB15348InvestigationalAmpreloxetine is under investigation in clinical trial NCT03750552 (Clinical Effect of TD-9855 for Treating snOH in Subjects With Primary Autonomic Failure).
Categories: Heterocyclic Compounds, 1-RingDihematoporphyrin ether
go.drugbank.com/drugs/DB15351InvestigationalDihematoporphyrin ether is under investigation in clinical trial NCT00118222 (High Light and Low Light Dose PDT in Glioma).
Synonyms: bis-1-(8-(1-hydroxyethyl)deuteroporphyrin-3-yl)ethyl etherCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsEvinacumab
go.drugbank.com/drugs/DB15354ApprovedInvestigationalEvinacumab is novel in its mechanism of action compared with other lipid-lowering therapies and therefore provides a unique and synergistic therapeutic option in the treatment of HoFH. … Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein 3 (ANGPTL3) and the first drug of its kind.
Categories: Angiopoietin-like 3 Inhibitor, Angiopoietin-like 3 InhibitorsJNJ-54175446
go.drugbank.com/drugs/DB15358InvestigationalJNJ-54175446 is under investigation in clinical trial NCT02933762 (A Study in Healthy Participants to Evaluate the Effect of JNJ-54175446 on Amyloid Biomarkers and Cytokine Profiles in Cerebrospinal Fluid
Categories: Heterocyclic Compounds, 1-RingCarfentanil, C-11
go.drugbank.com/drugs/DB15360InvestigationalCarfentanil, C-11 is under investigation in clinical trial NCT01899170 (Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain).
Categories: Heterocyclic Compounds, 1-RingSynonyms: Carfentanil, C-11LSZ-102
go.drugbank.com/drugs/DB15362InvestigationalLSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).
Categories: Heterocyclic Compounds, 1-RingPegbelfermin
go.drugbank.com/drugs/DB15365InvestigationalPegbelfermin is under investigation in clinical trial NCT03486899 (A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis).
Vopratelimab
go.drugbank.com/drugs/DB15378InvestigationalVopratelimab is under investigation in clinical trial NCT02904226 (JTX-2011 Alone and in Combination With Anti-PD-1 or Anti-CTLA-4 in Subjects With Advanced and/or Refractory Solid Tumors).
SAR-125844
go.drugbank.com/drugs/DB15382InvestigationalSAR-125844 is under investigation in clinical trial NCT01391533 (Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTeceleukin
go.drugbank.com/drugs/DB15389InvestigationalTeceleukin is under investigation in clinical trial NCT03610490 (Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Osteosarcoma, or Pancreatic Ductal Adenocarcinoma).
Categories: Interleukin-2