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Tauromustine
go.drugbank.com/drugs/DB19978ExperimentalTauromustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Tauromustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. Tauromustine has a monoisotopic molecular weight...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesArofylline
go.drugbank.com/drugs/DB20307ExperimentalThe usage of the INN stem '-fylline' in the name indicates that Arofylline is a N-methylated xanthine derivative. Arofylline has a monoisotopic molecular weight of 304.07 Da.
Cloperidone
go.drugbank.com/drugs/DB20327ExperimentalCloperidone is a small molecule drug. Cloperidone has a monoisotopic molecular weight of 398.15 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsMofarotene
go.drugbank.com/drugs/DB20333ExperimentalMofarotene is a small molecule drug. The usage of the INN stem '-arotene' in the name indicates that Mofarotene is a arotinoid derivative. Mofarotene has a monoisotopic molecular weight of 433.3 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNavamepent
go.drugbank.com/drugs/DB21096InvestigationalNavamepent is a small molecule drug. Navamepent is under investigation in clinical trial NCT02329743 (Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery). Navamepent has a monoisotopi...
Categories: P-glycoprotein inhibitorsNevadistinel
go.drugbank.com/drugs/DB21632InvestigationalThe usage of the INN stem '-stinel' in the name indicates that Nevadistinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist.
Sevabertinib
go.drugbank.com/drugs/DB21667ApprovedInvestigationalSevabertinib is a kinase inhibitor indicated for adult patients with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) whose tumors have HER2 (ERBB2) tyrosine kinase domain (TKD) activating mutations. Sevaber...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesDaraxonrasib
go.drugbank.com/drugs/DB22308ApprovedInvestigationalDaraxonrasib is an orally administered, multi-selective inhibitor of the RAS GTPase family used to treat metastatic pancreatic adenocarcinoma. It is a RAS(ON) tri-complex inhibitor that binds cyclophilin A and targets the active, GTP-bou...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesErgoloid mesylate
go.drugbank.com/drugs/DB01049ApprovedErgoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all de...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNeisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen
go.drugbank.com/drugs/DB10798ApprovedInvestigationalThe vaccine contains *N. meningitis* serogroup a capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are extracted from Corynebacterium diphtheriae