Search
Edetic acid
go.drugbank.com/drugs/DB00974ApprovedInvestigationalVet approvedA chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Categories: Compounds used in a research, industrial, or household settingSynonyms: EDTA, ion(4-), N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine)Arachidonic Acid Metabolism
smpdb.ca/view/SMP0000075MetabolicIn resting cells arachidonic acid is present in the phospholipids (especially phosphatidylethanolamine and phosphatidylcholine) of membranes of the body’s cells, and is particularly abundant in the brain … The enzyme 5-lipoxygenase leads to 5-HPETE, which in turn is used to produce the leukotrienes, hydroxyeicosatetraenoic acids (HETEs) and lipoxins.
Enzymes: Prostaglandin E synthaseAcetylsalicylic Acid Action Pathway
smpdb.ca/view/SMP0000083Drug actionIn addition to its anti-inflammatory properties, aspirin also acts as an analgesic, antipyretic and antithrombotic agent. … Platelets contain COX-1, a key enzyme in the production thromboxane A2 (TXA2), which is a potent inducer of platelet aggregation.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Acetylsalicylic acid · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthaseKetoprofen Action Pathway
smpdb.ca/view/SMP0000085Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Enzymes: Prostaglandin E synthaseMeloxicam Action Pathway
smpdb.ca/view/SMP0000106Drug actionThis in turn inhibits the calcium-dependent events, including PLA2 activation, involved in platelet activation and aggregation. … PGE2) involved in fever, pain, swelling and inflammation.
Enzymes: Prostaglandin E synthaseDiflunisal Action Pathway
smpdb.ca/view/SMP0000289Drug actionDiflunisal (also known as Dolobid) is a prostaglandin G/H synthase inhibitor that can inhibit prostaglandin G/H synthase 1 and 2 which prevent the production of prostaglandin. Therefore, diflunisal can be used for treating prostaglandin-...
Enzymes: Prostaglandin E synthaseFlurbiprofen Action Pathway
smpdb.ca/view/SMP0000697Drug actionDecreased prostaglandin synthesis in many animal model's cell is caused by presence of flurbiprofen. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Drugs: Glutamic acid · Glutathione · Flurbiprofen · Dinoprostone · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthaseMagnesium Salicylate Action Pathway
smpdb.ca/view/SMP0000698Drug actionDecreased prostaglandin synthesis in many animal model's cell is caused by presence of Magnesium Salicylate. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Magnesium salicylate +5 moreEnzymes: Prostaglandin E synthaseLornoxicam Action Pathway
smpdb.ca/view/SMP0000700Drug actionDecreased prostaglandin synthesis in many animal model's cell is caused by presence of Lornoxicam. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Enzymes: Prostaglandin E synthaseNepafenac Action Pathway
smpdb.ca/view/SMP0000702Drug actionDecreased prostaglandin synthesis in many animal model's cell is caused by presence of nepafenac. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Enzymes: Prostaglandin E synthase