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Benralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigationalBenralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils … [A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction.
Categories: Interleukin-5 Receptor alpha-directed Cytolytic Antibody, Interleukin 5 Receptor alpha-directed Antibody InteractionsProducts: FASENRA®, FASENRA 30 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖRSodium fluorophosphate
go.drugbank.com/drugs/DB09484ApprovedInvestigationalSodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Synonyms: Na MFPMixtures: PROPOLIS 200g, ATOMY PROPOLIS 200gTetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate
go.drugbank.com/drugs/DB14106ApprovedInvestigationalTetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]
Synonyms: Tetrakis (2-methoxyisobutyl isonitrile) copper (I) tetrafluoroborate, Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborateProducts: MON.MIBI KIT, 1.0 MG/FLAKON IV ENJEKSİYON İÇİN STERİL/APİROJEN LİYOFİLİZE TOZ, 5 ADET, MIBITEC 1 mg Kit für ein radioaktives ArzneimittelTocofersolan
go.drugbank.com/drugs/DB11635ApprovedD-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis [L2371]. … It was approved by the European Medicines Agency (EMA) in June 2009 under the market name Vedrop.
Synonyms: VITAMIN E POLYETHYLENE GLYCOL 1000 SUCCINATE, D-.ALPHA.-TOCOPHEROL POLYETHYLENE GLYCOL 1000 SUCCINATEMixtures: Eye Health Areds 2 FormulaPyritinol
go.drugbank.com/drugs/DB13084InvestigationalPyritinol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Categories: Heterocyclic Compounds, 1-RingProducts: ENCEFABOL® 200 MG SUSPENSION, ENCEFABOL(R) 200 MG SUSPENSIONHydroxocobalamin
go.drugbank.com/drugs/DB00200ApprovedInvestigationalHydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency.
Mixtures: TRIBEDOCE C/L, ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL (5+5)Categories: Vitamin B Complex, Heterocyclic Compounds, 1-RingCeftizoxime
go.drugbank.com/drugs/DB01332ApprovedWithdrawnThe drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. … A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acidDigitoxin
go.drugbank.com/drugs/DB01396ApprovedWithdrawnA cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Digimerck 0,1 mg/ml - Injektionslösung, Digimerck 0,07 mg - TablettenHemin
go.drugbank.com/drugs/DB03404ApprovedInvestigationalHemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsProducts: PANHEMATIN® POLVO ESTERIL LIOFILIZADO PARA INYECCIÓN 350 MG/ VIAL, NORMOSANG® 25MG/MLLenvatinib
go.drugbank.com/drugs/DB09078ApprovedInvestigationalIn particular, VEGF has been identified as a crucial regulator of both physiologic and pathologic angiogenesis and increased expression of VEGF is associated with a poor prognosis in many types of cancers … Most patients with thyroid cancer have a very good prognosis with treatment (98% 5 year survival rate) involving surgery and hormone therapy.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide