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Ammonia N-13
go.drugbank.com/drugs/DB09326ApprovedAmmonia N 13 Injection, USP is a positron emitting radiopharmaceutical that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging. … Ammonia N 13 Injection, USP is used for imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease
Synonyms: Ammonia N 13, Ammonia N-13Products: Ammonia N 13 N 13, Ammonia N 13Norethynodrel
go.drugbank.com/drugs/DB09371ApprovedA synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combin...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAmino acids
go.drugbank.com/drugs/DB09393InvestigationalMixture of amino acids ; used for parenteral nutrition in infants.
Products: AMINOSTERIL N-HEPA, AMINOVENOS N-PEDIATRICONavamepent
go.drugbank.com/drugs/DB21096InvestigationalNavamepent is a small molecule drug. Navamepent is under investigation in clinical trial NCT02329743 (Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery). Navamepent has a monoisotopi...
Categories: P-glycoprotein inhibitorsFilapixant
go.drugbank.com/drugs/DB21467ExperimentalFilapixant is a small molecule drug. The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist. Filapixant has a monoisotopic molecular weight of 521.17 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesNevadistinel
go.drugbank.com/drugs/DB21632InvestigationalThe usage of the INN stem '-stinel' in the name indicates that Nevadistinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist.
Sevabertinib
go.drugbank.com/drugs/DB21667ApprovedInvestigationalSevabertinib is a kinase inhibitor indicated for adult patients with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) whose tumors have HER2 (ERBB2) tyrosine kinase domain (TKD) activating mutations. Sevaber...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesDaraxonrasib
go.drugbank.com/drugs/DB22308ApprovedInvestigationalDaraxonrasib is an orally administered, multi-selective inhibitor of the RAS GTPase family used to treat metastatic pancreatic adenocarcinoma. It is a RAS(ON) tri-complex inhibitor that binds cyclophilin A and targets the active, GTP-bou...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesDarbepoetin alfa
go.drugbank.com/drugs/DB00012ApprovedInvestigationalHuman erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Pegfilgrastim
go.drugbank.com/drugs/DB00019ApprovedInvestigational[A187631] Due to the relatively short circulating half-life of filgrastim, a 20 kDa PEG moiety was covalently conjugated to the N-terminus of filgrastim (at the methionine residue) to develop longer-acting