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Glecaprevir
go.drugbank.com/drugs/DB13879ApprovedInvestigationalGlecaprevir is available as an oral combination therapy with [DB13878] under the brand name Mavyret. … As of June 2025, the FDA approved an expanded indication for Mavyret, making it the first and only direct-acting antiviral therapy approved for the treatment of both acute and chronic HCV in patients aged
QR-334
go.drugbank.com/drugs/DB05473ExperimentalThe symptom is associated with many diseases including Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s Disease, Cerebral Palsy, Parkinson's Disease, and Muscular Dystrophy.
Oxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalIt is often used as first-line therapy for OAB.[A185990] … [A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and
Diloxanide
go.drugbank.com/drugs/DB08792ExperimentalDiloxanide (as [Diloxanide furoate]) is an anti-protozoal drug used in the treatment of Entamoeba histolytica and some other protozoal infections.
Mafenide
go.drugbank.com/drugs/DB06795ApprovedVet approvedWithdrawnMafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the F...
Paromomycin
go.drugbank.com/drugs/DB01421ApprovedInvestigationalAn oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Clodronic acid
go.drugbank.com/drugs/DB00720ApprovedInvestigationalVet approvedClodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has de...
Clozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigationalClozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent.
anti-alpha5Beta1-integrin antibody
go.drugbank.com/drugs/DB05870Experimentalwell as other pro-angiogenic growth factors. … during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), as
AGS-16C3F
go.drugbank.com/drugs/DB17551InvestigationalAGS-16C3F is under investigation in clinical trial NCT02639182 (A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma). … AGS 16C3F is an intravenously administered, anti-ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody-drug conjugate.