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Naloxegol
go.drugbank.com/drugs/DB09049ApprovedInvestigationalIt was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain.
Histrelin
go.drugbank.com/drugs/DB06788ApprovedInvestigationalWithdrawnHistrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. … [L41715] Vantas was later discontinued by Endo Pharmaceuticals Inc. on September 21, 2021.
Synonyms: [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormoneMicturition urgency
go.drugbank.com/conditions/DBCOND0018872Synonyms: Urgency to pass urine, Must hurry to pass urineDextropropoxyphene
go.drugbank.com/drugs/DB00647ApprovedIllicitWithdrawnIt is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. … The drug is often referred to as the general form, "propoxyphene", however only the dextro-isomer (dextropropoxyphene) has any analgesic effect.
Products: Novo-propoxyn Cap 65mgPhenylpropanolamine
go.drugbank.com/drugs/DB00397ApprovedVet approvedWithdrawnIt has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes. … Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor.
Mixtures: COUGH - EN, COUGH - EN PLUSEtidronic acid
go.drugbank.com/drugs/DB01077ApprovedInvestigational[A203111] Etidronic acid was granted FDA approval on 1 September 1977.[L13901] … [A1923] Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]
Mixtures: Mylan-eti-cal CarepacProducts: Didronel Inj 50mg/mlZanubrutinib
go.drugbank.com/drugs/DB15035ApprovedInvestigational[L10169] It is currently marketed under the trade name BRUKINSA™ and is available as oral capsules. … [L39367] In September 2021, zanubrutinib was granted another accelerated approval for the treatment of relapsed or refractory marginal zone lymphoma who have received at least one anti-CD20-based regimen
Products: CAPSULE 80MGMedium-chain triglycerides
go.drugbank.com/drugs/DB13959ApprovedInvestigationalMCTs are found in natural foods, such as coconut oil, palm kernel oil, and raw coconut meat. … [A246688] MCTs are used in parenteral nutrition therapy: they serve as a source of calories and essential fatty acids in conditions associated with malnutrition and malabsorption.[L41340]
Mixtures: SMOFKABIVEN EF, LIPOFUNDIN MCT/LCT %10 VIT E INFUZYON ICIN YAG EMULSUYONU, 100 MLSARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)
go.drugbank.com/drugs/DB18705Approved[L48902,L48907] Bimervax was issued marketing authorization in the EU in March 2023 for use as a booster dose in patients who have previously received an mRNA COVID-19 vaccine.[L48907] … [L48902] It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023.
Sufentanil
go.drugbank.com/drugs/DB00708ApprovedInvestigationalIt is administered by the intravenous, epidural and sublingual routes. … Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent.