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Flavoxate is a muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia. A drug that has been used in various urinary syndromes and as an antispasmodic.
- Mechanism
- Curator reviewed
Flavoxate acts as a direct antagonist at muscarinic acetylcholine receptors in cholinergically innervated organs. Its anticholinergic-parasympatholytic action reduces the tonus of smooth muscle in the bladder, effectively reducing the number of required voids, urge incontinence episodes, urge severity and improving retention, facilitating increased volume per void.
- Primary indication
- For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.Curator reviewed · 24 structured indications
- Formula / weight
- C24H25NO4 · 391.4596 g/mol (avg)
- First approval
- Canada, 1997 · United States, 1970
Resolves to
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Which drugs share a target with Flavoxate, and which of those have an active Phase 3 trial?