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Displaying results 2071 - 2080 of 10000 in total
  1. Drug

    Brensocatib

    go.drugbank.com/drugs/DB15638
    Approved

    [A274348] Brensocatib is a first-in-class dipeptidyl peptidase 1 (DPP1) inhibitor that inhibits neutrophil serine proteases, addressing a key driver of this inflammation. … [A274348,A274343] It reduces exacerbations and slows lung function decline, offering a targeted approach to managing NCFB.

    Categories: MATE 1 Inhibitors, MATE 2 InhibitorsSynonyms: (S)-N-((S)-1-Cyano-2-(4-(3-methyl-2-oxo-2,3-dihydrobenzo-(d)oxazol-5-yl)phenyl)ethyl)-1,4-oxazepane-2-carboxamide
  2. Drug

    Luvadaxistat

    go.drugbank.com/drugs/DB16067
    Investigational

    Luvadaxistat is under investigation in clinical trial NCT03214588 (Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia).

    Categories: D-Amino Acid Oxidase InhibitorSynonyms: 3(2H)-PYRIDAZINONE, 4-HYDROXY-6-(2-(4-(TRIFLUOROMETHYL)PHENYL)ETHYL)-, 4-HYDROXY-6-(2-(4-(TRIFLUOROMETHYL)PHENYL)ETHYL)-2,3-DIHYDROPYRIDAZIN-3-ONE
  3. Drug

    CFG-920

    go.drugbank.com/drugs/DB19193
    Investigational

    CFG-920 is under investigation in clinical trial NCT04060394 (Dose-escalation and Efficacy Study of Lae001/prednisone Plus Afuresertib Patients With M-crpc).

    Synonyms: 1-(2-CHLORO-4-PYRIDINYL)-3-(4-METHYL-3-PYRIDINYL)-2-IMIDAZOLIDINONE, 2-imidazolidinone, 1-(2-chloro-4-pyridinyl)-3-(4-methyl-3-pyridinyl)-
  4. Drug

    Fidrisertib

    go.drugbank.com/drugs/DB18064
    Investigational

    Synonyms: (r)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo(1,2-b)pyridazin-4-yl)piperazine-1-carboxylate, 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2-b)pyridazin-4-yl)-, (3r)-tetrahydro-3-furanyl ester
  5. Drug

    Diamino-N-[(4S)-5-anilino-4-{[(2S)-2-{[(1R)-1-carboxyethyl]amino}-4-phenylbutanoyl]amino}-5-oxopentyl]methaniminium

    go.drugbank.com/drugs/DB02747
    Experimental

    Synonyms: Diamino-N-[(4S)-5-anilino-4-{[(2S)-2-{[(1R)-1-carboxyethyl]amino}-4-phenylbutanoyl]amino}-5-oxopentyl]methaniminium
  6. Drug

    2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE

    go.drugbank.com/drugs/DB07618
    Experimental

    Synonyms: 2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE
  7. Drug

    Pipequaline

    go.drugbank.com/drugs/DB13991
    Experimental

    However, it presents a significant set of anxiolytic properties with a very little sedative, amnestic or anticonvulsant effect. … Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed.

    Synonyms: 2-Phenyl-4-(2-(4-piperidyl)ethyl)quinolineCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Amoscanate

    go.drugbank.com/drugs/DB21356
    Experimental

    Amoscanate is a small molecule drug. Amoscanate has a monoisotopic molecular weight of 271.04 Da.

    Synonyms: 4-isothiocyanato-4'-nitrodiphenylamine, P-(p-nitroanilino)phenyl isothiocyanate
  9. Drug

    Isoluminol

    go.drugbank.com/drugs/DB02041
    Experimental

    Synonyms: 4-aminophthalhydrazideCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  10. Drug

    Rosaramicin

    go.drugbank.com/drugs/DB20624
    Experimental

    Rosaramicin is a small molecule drug. Rosaramicin has a monoisotopic molecular weight of 581.36 Da.

    Synonyms: 4'-deoxycirramycin a1, Cirramycin a1, 4'-deoxy-