Fidrisertib

DB18064InvestigationalSmall molecule

Fidrisertib: Overview.

Mechanism: Pharmacologically active on Activin receptor type-1
Curator reviewed
Formula / weight: C₃₁H₄₂N₆O₄ · 562.715 g/mol (avg)
Also known as: (r)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo(1,2-b)pyridazin-4-yl)piperazine-1-carboxylate · 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2-b)pyridazin-4-yl)-, (3r)-tetrahydro-3-furanyl ester
Code names: BLU-782

Resolves to

Compound

Structure

InChIKeySWVYYNLRVIYURK-AREMUKBSSA-NSMILESCCOC1(CCN(CC1)C(C)C)C1=CC=C(N=C1)C1=CN2N=CC=C(N3CCN(CC3)C(=O)O[C@@H]3CCOC3)C2=C1

Targets

What you can answer from here — as of September 12, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Fidrisertib, and which of those have an active Phase 3 trial?

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