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Fosdenopterin
go.drugbank.com/drugs/DB16628Approved[A230088,L32163] Patients with MoCD may present with metabolic acidosis, intracranial hemorrhage, feeding difficulties, and significant neurological symptoms such as muscle hyper- and hypotonia, intractable … In July 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended fosdenopterin be granted marketing authorization under exceptional circumstances for the treatment of patients
Recombinant stabilized RSV B prefusion F antigen
go.drugbank.com/drugs/DB18714ApprovedInvestigational[L48066] Abrysvo was first approved by the FDA in May 2023 for use in patients ≥60 years of age, and received subsequent approval in August 2023 for use in pregnant individuals for the protection of … [L49560] It is the first RSV vaccine approved for use in pregnant patients to prevent RSV in infants.[L49555]
Evening primrose oil
go.drugbank.com/drugs/DB11358ApprovedNutraceuticalEvening primrose oil comes from the extraction from _Oenothera biennis_ seeds and it is commonly used as an alternative source for omega-6 essential fatty acids. … [A33131] Evening primrose oil has been filled for the FDA by Humanetics Corporation on April 2000 to be a new dietary ingredient but its current status is "Inadequate basis for expectation of safety".
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 Enzyme InhibitorsPhenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approved[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications … [A188826,A188832] Clinicians are advised to initiate therapeutic drug monitoring in patients who require phenytoin since even small deviations from the recommended therapeutic range can lead to suboptimal
Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein substratesSynonyms: PR-122 (redox-phenytoin)Enfuvirtide
go.drugbank.com/drugs/DB00109ApprovedInvestigationalEnfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseRimantadine
go.drugbank.com/drugs/DB00478ApprovedAn RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Categories: Antiinfectives for Systemic UseSulindac
go.drugbank.com/drugs/DB00605ApprovedInvestigationalThere is evidence from some studies that sulindac may be associated with fewer gastrointestinal side effects than other NSAIDs, except for the cyclooxygenase-2 (COX-2) inhibitor drug class. … Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions.
Synonyms: cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid, (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acidDL-dimyristoylphosphatidylglycerol
go.drugbank.com/drugs/DB11284ApprovedDL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Tridihexethyl
go.drugbank.com/drugs/DB00505ApprovedWithdrawnTridihexethyl is an antimuscarinic, anticholinergic drug. Tridihexethyl is no longer available in the US market.
Categories: Drugs for Functional Gastrointestinal DisordersDipotassium phosphate
go.drugbank.com/drugs/DB09414ApprovedInvestigationalDipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Mixtures: Instillation Medium for Immucyst, Isolyte P in Dextrose