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Pasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalPasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Synonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)International brands: Signifor LARMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalIt is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
Mixtures: VELMETIA LP, Vildagliptin/Metformin 1A Pharma 50 mg/850 mg – FilmtablettenCategories: Drugs Used in DiabetesBupropion
go.drugbank.com/drugs/DB01156ApprovedInvestigational[L6562,A179038,A179050] The combination of naltrexone and bupropion was shown to result in a statistically significant weight loss, with a mean change in body weight of -6.3% compared to -1.3% for placebo … [A178816] Bupropion is sometimes used as an add-on agent to first-line treatments of depression such as selective serotonin reuptake inhibitor (SSRI) medications when there is a treatment-failure or
Products: WELLBUTRIN LR, Aplenzin ERGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigationalGanirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999.
Products: NOVOLEX 0.25 MG/0.5 ML SOLUCIÓN INYECTABLE EN JERINGA PRECARGADA, Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer FertigspritzeSus scrofa skin
go.drugbank.com/drugs/DB10606ApprovedSus scrofa skin or pelt is used in allergenic testing.
Products: PiGe ll Real Skin Eye, PiGe ll Real Skin Neck PackDocusate
go.drugbank.com/drugs/DB11089ApprovedStill docusate is available in over-the-counter products as a common laxative. … Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201].
Mixtures: EX-lax Gentle Strength, EX-lax Light Formula Lax W Stool Soften TabProducts: EX-lax Stool Softener - Tab 100 mg, Lax-A SoftAmmonium lactate
go.drugbank.com/drugs/DB06768ApprovedAmmonium lactate is the ammonium salt of lactic acid.
Products: Lac-Hydrin, Lac Hydrin CreamColloidal oatmeal
go.drugbank.com/drugs/DB11286ApprovedNutraceuticalIt is available in topical products as a skin soothing agent. … Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity.
Mixtures: Infinite Aloe All-IN-one Skin CareProducts: La Roche Posay Laboratoire Dermatologique Lipikar Eczema Relief, La Roche Posay Laboratoire Dermatologique Lipikar Eczema Soothing ReliefBendamustine
go.drugbank.com/drugs/DB06769ApprovedInvestigationalBendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). … Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, BENDAMUSTINA EGPipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnHowever, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. … Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics.
Products: Piportil L4, PIPORTIL ® L-4SOLUCION INYECTABLE AL 2.5% (100 MG).