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(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE
go.drugbank.com/drugs/DB07211ExperimentalSynonyms: (2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDETD-0903
go.drugbank.com/drugs/DB16463InvestigationalTD-0903 was investigated in clinical trials for its potential to treat acute lung injury (ALI) associated with COVID-19, including NCT04350736, NCT05091723 (a pharmacokinetics study in healthy participants … with supplemental oxygenation), and NCT04402866 (focused on ALI and lung inflammation associated with COVID-19)
Synonyms: (3-(DIMETHYLAMINO)AZETIDIN-1-YL)((6S)-2-(6-(2-ETHYL-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-5-(PROPAN-2-YL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZO(4,5-C)PYRIDIN-6-YL)METHANONE, (S)-(3-(DIMETHYLAMINO)AZETIDIN-1-YL)(2-(6-(2-ETHYL-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-5-ISOPROPYL-4,5,6,7-TETRAHYDRO-3H-IMIDAZO(4,5-C)PYRIDIN-6-YL)METHANONECategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingABBV-744
go.drugbank.com/drugs/DB19199InvestigationalSynonyms: 1H-PYRROLO(2,3-C)PYRIDINE-2-CARBOXAMIDE, N-ETHYL-4-(2-(4-FLUORO-2,6-DIMETHYLPHENOXY)-5-(1-HYDROXY-1-METHYLETHYL)PHENYL)-6,7-DIHYDRO-6-METHYL-7-OXO-, N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1h-pyrrolo(2,3-c)pyridine-2-carboxamideCategories: Heterocyclic Compounds, 1-RingSafusidenib
go.drugbank.com/drugs/DB18745InvestigationalSynonyms: (2E)-3-[1-[[5-(1-Fluoro-1-methylethyl)-3-(2,4,6-trichlorophenyl)-4-isoxazolyl]carbonyl]-3-methyl-1H-indol-4-yl]-2-propenoic acid, 2-Propenoic acid, 3-[1-[[5-(1-fluoro-1-methylethyl)-3-(2,4,6-trichlorophenyl)-4-isoxazolyl]carbonyl]-3-methyl-1H-indol-4-yl]-, (2E)-Oxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A796,A797] This is an effective combination treatment both as a first-line treatment and in patients refractory to an initial fluorouracil and leucovorin combination. … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin.
Synonyms: (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUM, L-OHPCategories: OCT2 Substrates with a Narrow Therapeutic IndexIMT-288
go.drugbank.com/drugs/DB19068InvestigationalIMT-288 is under investigation in clinical trial NCT01730638 (Immunotep for Patients With Medullary Thyroid Carcinoma.).
Synonyms: (4R)-5-(((1R)-1-CARBAMOYL-5-((2-((4-(2-(1H-IMIDAZOL-5-YL)ETHYLAMINO)-4-OXO-BUTANOYL)AMINO)ACETYL)AMINO)PENTYL)AMINO)-4-(((2R)-2-(((2R)-3-(4-HYDROXYPHENYL)-2-((2-(4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAZACYCLODODEC, D-LYSINAMIDE, N-((4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAAZACYCLODODEC-1-YL)ACETYL)-D-TYROSYL-N6-(N-(4-((2-(1H-IMIDAZOL-4-YL)ETHYL)AMINO)-1,4-DIOXOBUTYL)GLYCYL)-D-LYSYL-D-.ALPHA.Londamocitinib
go.drugbank.com/drugs/DB19190InvestigationalLondamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high
Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-Fallypride F-18
go.drugbank.com/drugs/DB19254InvestigationalFallypride F-18 is under investigation in clinical trial NCT00846040 (Reduced Carbohydrate Versus Fat in Obese Subjects).
Synonyms: Benzamide, 5-(3-(fluoro-18f)propyl)-2,3-dimethoxy-n-(((2s)-1-(2-propen-1-yl)-2-pyrrolidinyl)methyl)-, F-18 fallyprideTBI-223
go.drugbank.com/drugs/DB18911InvestigationalTBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Synonyms: CARBAMIC ACID, N-(((5S)-3-(3-FLUORO-4-(2-OXA-6-AZASPIRO(3.3)HEPT-6-YL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL)-, METHYL ESTERFidrisertib
go.drugbank.com/drugs/DB18064InvestigationalSynonyms: (r)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo(1,2-b)pyridazin-4-yl)piperazine-1-carboxylate, 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2-b)pyridazin-4-yl)-, (3r)-tetrahydro-3-furanyl ester