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Oxymetazoline
go.drugbank.com/drugs/DB00935ApprovedInvestigationalThe topical formulation of the drug is used to treat persistent facial redness in adults. … [L15057] In July 2020, the FDA approved the use of an ophthalmic formulation of oxymetazoline (Upneeq) in adults with acquired blepharoptosis, or ptosis, making it the first FDA-approved medical treatment
Synonyms: 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenolInternational brands: Genasal Nasal Spray Up to 12 Hour ReliefHistrelin
go.drugbank.com/drugs/DB06788ApprovedInvestigationalWithdrawn[L41715] The Vantas product was approved by the FDA in October 2004 for the palliative treatment of this condition. … As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by the FDA in May 2007).[L41700]
Categories: Gonadotropin Releasing Hormone Receptor Agonist, Gonadotropin Releasing Hormone Receptor AgonistsVelmanase alfa
go.drugbank.com/drugs/DB12374ApprovedInvestigationalVelmanase alfa has an amino acid sequence of the monomeric protein identical to the naturally occurring human alpha-mannosidase. … The resulting accumulation of sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and skeletal deterioration, such as skeletal abnormalities, motor function
Alvimopan
go.drugbank.com/drugs/DB06274ApprovedInvestigationalIt is used to avoid postoperative ileus following small or large bowel resection and accelerates the gastrointestinal recovery period.
Categories: Peripheral Opioid Receptor AntagonistsPolycarbophil
go.drugbank.com/drugs/DB09311ApprovedWithdrawnPolycarbophil calcium is a stool stabilizer used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea. … The material possesses exceptionally high water-binding capacity. is not absorbed, does not interfere with the activity of digestive enzymes or intestinal absorption, possesses satisfactory stability,
Clonazepam
go.drugbank.com/drugs/DB01068ApprovedIllicitInvestigational[FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses. … in the treatment of the aforementioned medical conditions.
Synonyms: 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one, 5-(2-chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-oneProducts: RIVOTRIL ® TABLETAS DE 2.0 MG.Lusutrombopag
go.drugbank.com/drugs/DB13125ApprovedInvestigationalLusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). … Lusutrombopag was approved by the FDA on July 31st, 2018 for the same therapeutic indication under the market name Mulpleta.
Categories: Thrombopoietin Receptor AgonistTechnetium Tc-99m red blood cells
go.drugbank.com/drugs/DB09493ApprovedWithdrawnAutologous red blood cells are radiolabeled with sodium pertechnetate Tc 99m in the reaction vial. … It is suggested that _in vitro_ labelling improves the heart-to-background ratio during imaging [A32181].
Synonyms: Technetium Tc 99m red blood cells, Technetium Tc-99m red blood cellDienogest
go.drugbank.com/drugs/DB09123ApprovedInvestigationalDienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself.
Categories: Sex Hormones and Modulators of the Genital SystemProducts: DIENOGEST E ETINILESTRADIOLO DOCNalmefene
go.drugbank.com/drugs/DB06230ApprovedInvestigationalWithdrawn[L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. … [L40684] The nasal spray formulation of nalmefene was approved by the FDA in May 2023.[L46511]