Velmanase alfa

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Velmanase alfa
Accession Number
DB12374
Description

Recombinant Human Alpha Mannosidase has been investigated for the treatment of Alpha Mannosidosis and Alpha-Mannosidosis.

Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Other protein based therapies
Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
  • Lamazym
  • Recombinant Human Alpha Mannosidase
  • Rhlaman

Pharmacology

Indication
Not Available
Associated Conditions
Contraindications & Blackbox Warnings
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Categories

ATC Codes
A16AB15 — Velmanase alfa
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Chemical Identifiers

UNII
M91TG242P2
CAS number
1492823-75-2

References

General References
  1. AIFA Product Information: Lamzede (velmanase alfa) powder for solution for infusion [Link]
PubChem Substance
347911328
Wikipedia
Velmanase_alfa

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingTreatmentAlpha-Mannosidosis1
3CompletedTreatmentAlpha-Mannosidosis2
3Enrolling by InvitationTreatmentAlpha-Mannosidosis1
3Not Yet RecruitingTreatmentAlpha-Mannosidosis1
2CompletedTreatmentAlpha-Mannosidosis2
2Unknown StatusTreatmentAlpha Mannosidosis / Alpha-Mannosidosis1
1CompletedTreatmentAlpha Mannosidosis / Alpha-Mannosidosis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Powder, for solutionIntravenous10 MG
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on October 20, 2016 16:07 / Updated on October 21, 2020 05:28

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