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Eptinezumab
go.drugbank.com/drugs/DB14040ApprovedInvestigational[F94,A33105,A33106,A33108] It was approved by the FDA in February 2020 for the preventive treatment of migraine headaches in adults.[L12318] … Eptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (_Pichia pastoris_) and developed by Lundbeck Seattle Biopharmaceuticals.
Products: VYEPTI CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/ML, Vyepti® 100 mg/mL concentrate for solution for infusionEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalA prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.
Categories: Prostaglandins ISynonyms: Prostaglandin I2Pitolisant
go.drugbank.com/drugs/DB11642ApprovedInvestigational[L8063] Narcolepsy is a chronic neurological disorder that affects 1 in 2,000 individuals and is characterized by excessive daytime sleepiness, abnormal REM sleep manifestations, sleep paralysis and hypnagogic … [A32024] Pitolisant therapy was also effective in treating refractory sleepiness in adolescent patients with narcolepsy, where it decreased ESS score and increased the mean sleep onset latency.
Indium In-111 pentetreotide
go.drugbank.com/drugs/DB11835ApprovedIndium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.
Mixtures: Kit for the Preparation of Indium In 111 PentetreotideSynonyms: Indium In 111 Pentreotide, Indium In 111 pentetreotideBismuth subgallate
go.drugbank.com/drugs/DB13909ApprovedIt is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. … internal deodorant where it is often employed as the primary active ingredient.
Tolcapone
go.drugbank.com/drugs/DB00323ApprovedInvestigationalWithdrawnTolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. … It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Microcrystalline cellulose
go.drugbank.com/drugs/DB14158ApprovedInvestigationalA polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. … As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
Categories: Compounds used in a research, industrial, or household settingMethohexital
go.drugbank.com/drugs/DB00474ApprovedAn intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Synonyms: α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid, 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acidZapomeran
go.drugbank.com/drugs/DB21761Approved[L52585,L52590] Previously marketed in Japan, in December 2024 Kostaive became the first self-amplifying mRNA COVID-19 vaccine to receive approval from the European Commission.[L52580,L52585] … Zapomeran, marketed under the brand name Kostaive (ARCT-154), is a self-amplifying mRNA COVID-19 vaccine for individuals 18 years and older.
Streptomycin
go.drugbank.com/drugs/DB01082ApprovedInvestigationalVet approvedStreptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s. … adjunctive treatment in cases of multi-drug resistant tuberculosis.
Synonyms: 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside