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Aminoflavone
go.drugbank.com/drugs/DB19077InvestigationalAminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesArketamine
go.drugbank.com/drugs/DB19150InvestigationalArketamine is under investigation in clinical trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of PCN-101 in TRD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSubstance P
go.drugbank.com/drugs/DB19198InvestigationalSubstance P is under investigation in clinical trial NCT03738878 (Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1).
Categories: Substance P, antagonists & inhibitorsSynonyms: Substance P, Neurokinin pCamizestrant
go.drugbank.com/drugs/DB19218ApprovedInvestigationalCamizestrant is an oral selective estrogen receptor degrader (SERD) and estrogen receptor (ER) antagonist used in combination with a CDK4/6 inhibitor to treat hormone receptor-positive, HER2-negative locally advanced or metastatic breast...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSorbitan monolaurate
go.drugbank.com/drugs/DB20157InvestigationalSorbitan monolaurate is a small molecule drug. Sorbitan monolaurate has a monoisotopic molecular weight of 346.24 Da.
Categories: P-glycoprotein inhibitorsImnopitant
go.drugbank.com/drugs/DB21456ExperimentalThe usage of the INN stem '-pitant' in the name indicates that Imnopitant is a neurokinin NK1 (substance P) receptor antagonist. Imnopitant has a monoisotopic molecular weight of 550.22 Da.
Zastaprazan
go.drugbank.com/drugs/DB21524InvestigationalZastaprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Zastaprazan is a proton pump inhibitor, not dependent on acid activation. Zastaprazan is under investigation in clinical trial NCT058148...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesLimnetrelvir
go.drugbank.com/drugs/DB21677ExperimentalLimnetrelvir is a small molecule drug. The usage of the INN stem '-trelvir' in the name indicates that Limnetrelvir is a antiviral 3CL protease inhibitor. Limnetrelvir has a monoisotopic molecular weight of 557.17 Da.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 SubstratesEnerisant
go.drugbank.com/drugs/DB20605ExperimentalEnerisant is a small molecule drug. The usage of the INN stem '-isant' in the name indicates that Enerisant is a histamine H3 receptor antagonist. Enerisant has a monoisotopic molecular weight of 398.23 Da.
Categories: P-glycoprotein substratesBesigomsin
go.drugbank.com/drugs/DB20894ExperimentalBesigomsin is a small molecule drug. Besigomsin has a monoisotopic molecular weight of 416.18 Da.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates