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Ifosfamide
go.drugbank.com/drugs/DB01181ApprovedInvestigationalIfosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.
Products: UROMIDA® 2 G, HOLOXAN®2 G.Tucatinib
go.drugbank.com/drugs/DB11652ApprovedInvestigationalTucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable or metastatic HER-2 positive breast cancer. … It was developed by Seattle Genetics and approved by the FDA on April 17, 2020.
Products: TUKYSA 50 mg film-coated tablets, TUKYSA 150 mg film-coated tabletsSodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnIt is most effective in active progressive rheumatoid arthritis and of little or no value in the presence of extensive deformities or in the treatment of other forms of arthritis. … Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL.
Products: MIOCRIN 50 MG, MYOCRISIN INJECTION 20 MG (4% W/V)Propolis wax
go.drugbank.com/drugs/DB11355ApprovedInvestigationalPropolis wax is naturally produced by honeybees by mixing the resin or exudate collected from tree buds, sap flows, or other botanical sources with beeswax that contains fatty acids and bee enzymes.
Mixtures: Dr.bro MAN OF SENSE Mans CleanserLumacaftor
go.drugbank.com/drugs/DB09280ApprovedInvestigationalPrior to the development of lumacaftor and [DB08820] (Kalydeco), management of CF primarily involved therapies for the control of infections, nutritional support, clearance of mucus, and management of … of CFTR protein.
Esketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigationalEsketamine is the s-enantiomer of [Ketamine]. Ketamine is a mixture of two enantiomers (mirror image molecules). This is the first time that the FDA has approved esketamine for any use. … The intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to
Synonyms: (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanoneProducts: Ketanest S 5 mg/ml - Ampullen, Ketanest S 25 mg/ml - AmpullenMicrocrystalline cellulose
go.drugbank.com/drugs/DB14158ApprovedInvestigationalIt is the chief constituent of plant fibers, cotton being the purest natural form of the substance.
Categories: Compounds used in a research, industrial, or household settingLazertinib
go.drugbank.com/drugs/DB16216ApprovedInvestigational[A264289] It was approved by the FDA on August 19, 2024.[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184] … [A264299, A264304] Lazertinib was first approved in South Korea on January 18, 2021, for the treatment of _EGFR_ T790M mutation-positive non-small cell lung cancer (NSCLC) with EGFR mutations.
Bempedoic acid
go.drugbank.com/drugs/DB11936ApprovedInvestigationalCaused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. … A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous
Lisdexamfetamine
go.drugbank.com/drugs/DB01255ApprovedInvestigationalLisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid L-lysine.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: SAMEXID 70 MG, VYVANSE CAPSULES 20 mg