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Azelaic acid
go.drugbank.com/drugs/DB00548ApprovedInvestigationalAzelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis. … It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear.
Bimekizumab
go.drugbank.com/drugs/DB12917ApprovedInvestigational[L39665,L39680] It is the first IL-17 inhibitor to target both IL-17A and IL-17F. … of moderate-to-severe psoriasis,[A244450,A244455] likely owing to its dual inhibition of both IL-17A and IL-17F.
Carisoprodol
go.drugbank.com/drugs/DB00395Approvedfor abuse in addition to a low risk of dependence [L5074]. … In January 2012, this drug was classified as a Schedule IV substance under the controlled substances act in several US states due to alarming rates of abuse [A176062, A176077] despite having a low potential
Thioproperazine
go.drugbank.com/drugs/DB01622ApprovedIt is used for the treatment of all types of acute and chronic schizophrenia, including those which did not respond to the usual neuroleptics; manic syndromes.
Categories: Adrenergic alpha-1 Receptor Antagonists, Dopamine D2 Receptor AntagonistsPentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnThe reacting solution is chilled to precipitate the PETN. … It is recognized by the FDA to be a coronary vasodilator in the treatment of heart conditions such as angina [L2395].
Synonyms: TEN, Tetranitrato de pentaeritritiloPolycarbophil
go.drugbank.com/drugs/DB09311ApprovedWithdrawnPolycarbophil calcium is a stool stabilizer used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea. … The material possesses exceptionally high water-binding capacity. is not absorbed, does not interfere with the activity of digestive enzymes or intestinal absorption, possesses satisfactory stability,
Carbamazepine
go.drugbank.com/drugs/DB00564ApprovedInvestigationalIt was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. … [L1335] Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.[A180319]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: CARBAZOL DE 200 MG, TEGRETOL RETARD DE 200 MGPaltusotine
go.drugbank.com/drugs/DB16277ApprovedInvestigationalPaltusotine is a selective somatostatin receptor agonist: It mimics the biological actions of endogenous somatostatin, which activates the somatostatin 2 receptor (SST2) to block the secretion of growth … [A274476] Paltusotine was approved by the FDA on September 25, 2025 for the treatment of acromegaly in adults.[L54061]
Categories: Somatostatin Receptor AgonistsLenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigationalzone lymphoma in selected patients. … [L16028] Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enroll in the lenalidomide Risk Evaluation and Mitigation Strategy (REMS) program to ensure
Linagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin was approved by the FDA on May 2, 2011[L9557]. … Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes [L9557].