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Ebola Zaire vaccine (live, attenuated)
go.drugbank.com/drugs/DB15595ApprovedInvestigational(PHEIC) status on the West Africa Ebola outbreak. … The mortality rate of the Zaire species is about 80%.
Synonyms: Ebola Zaire Vaccine (rVSV∆G-ZEBOV-GP, live), Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GPPhentolamine
go.drugbank.com/drugs/DB00692ApprovedInvestigationaldoses of phentolamine. … [A261781, A261786] It has several therapeutic uses, including the treatment of hypertensive episodes, prevention of norepinephrine-induced extravasation, diagnosis of pheochromocytoma, reversal of soft-tissue
Thallous chloride
go.drugbank.com/drugs/DB09316ApprovedWithdrawnIt is used for diagnosis of heart and parathyroid problems. … Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation of thallium from its ores.
Metamfetamine
go.drugbank.com/drugs/DB01577ApprovedIllicitInvestigationalWithdrawnMetamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine group of sympathomimetic amines. … The FDA withdrew its approval for the use of all parenteral drug products containing methamphetamine hydrochloride, a metamfetamine salt.[L43942]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDocetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigationalDocetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel].
Products: LILDOCEX 40 MG/ ML (80 MG/2 ML), LILDOCEX® 40 MG/ ML (20 MG/0.5 ML)Casirivimab
go.drugbank.com/drugs/DB15941ApprovedInvestigational[A221495] On November 21 2020, the FDA authorized emergency approval of REGEN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and older. … Casirivimab is a monoclonal antibody combined with [Imdevimab] in Regeneron's antibody cocktail known as REGN-COV2 for the treatment of COVID-19.
Azacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigationalmyeloid leukemia (AML), two types of cancer characterized by the presence of aberrant DNA methylation. … One of them is the induction of cytotoxicity. As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis.
Products: Azacitidin EVER Pharma 25 mg/ml Pulver zur Herstellung einer Injektionssuspension, AZACITIDINA EGBrexpiprazole
go.drugbank.com/drugs/DB09128ApprovedInvestigational[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015. … [A182186] Currently approved for the treatment of depression, schizophrenia, and agitation associated with dementia due to Alzheimer’s disease, brexpiprazole has also been investigated in other psychiatric
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: REXULTI (BREXPIPRAZOLE) TABLETS 1 MG, REXULTI (BREXPIPRAZOLE) TABLETS 2 MGPrasugrel
go.drugbank.com/drugs/DB06209ApprovedInvestigationalR-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing activation of the GPIIb/IIIa receptor complex. … As a result, inhibition of ADP-mediated platelet activation and aggregation occurs.
Products: PRASUGREL BETA 5 MG FTA, Prasulan 5 mg-FilmtablettenZotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawnIn the EMA, by 2015 it was under pharmacovigilance studies for the potential treatment of acute renal failure.[L1314] … [L1082] When the analysis of antipsychotics was retaken in 2016 by the FDA, zotepine did not reach the threshold effect to be further studied.[L1313].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: ZOLEPTIL © 50 MG TABLETAS RECUBIERTAS.