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Trametinib
go.drugbank.com/drugs/DB08911ApprovedInvestigationalTrametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor. It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada ...
Categories: Genito Urinary System and Sex HormonesOsilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigationalOsilodrostat is an inhibitor of 11β-hydroxylase (also referred to as CYP11B1), the enzyme that catalyzes the final step in the biosynthesis of endogenous cortisol. It is used to lower circulating cortisol levels in the treatment of Cushi...
Categories: Sex Hormones and InsulinsDihydromorphine
go.drugbank.com/drugs/DB01565ExperimentalIllicitA semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]
Categories: Semi-synthetic OpioidsHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnCertain population subgroups in these areas, however, are at high risk (see Indications and Clinical Use). … The incubation period may be as long as 6 months, followed by a very complex clinical course of an acute or chronic nature, often leading to hospitalization.
Categories: Complex MixturesDental Mesenchymal Pulp Stem Cells
go.drugbank.com/drugs/DB15737InvestigationalDental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties.
Synonyms: Dental Pulp Mesenchymal Stem Cells, Allogenic Human Dental Pulp Stem CellsCelecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigationalCelecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other
Categories: Genito Urinary System and Sex HormonesMethimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigationalMethimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones. It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those f...
Categories: Sex Hormones and InsulinsRosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigational[A181523] This last point results in less risk of drug-drug interactions compared to [atorvastatin], [lovastatin], and [simvastatin], which are all extensively metabolized by Cytochrome P450 (CYP) 3A4,
Categories: Genito Urinary System and Sex HormonesBromocriptine
go.drugbank.com/drugs/DB01200ApprovedInvestigationalWithdrawnBromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indica...
Categories: Genito Urinary System and Sex Hormones