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Displaying results 2181 - 2190 of 10000 in total
  1. Drug

    PTX-100

    go.drugbank.com/drugs/DB18125
    Investigational

    Synonyms: 2-{[2-benzyl-4-(5-methyl-3H-imidazol-4-ylmethyl)-3-oxo-piperazine-1-carbonyl]- amino}-4methyl-pentanoic acid
  2. Drug

    Eragidomide

    go.drugbank.com/drugs/DB19242
    Investigational

    Eragidomide is under investigation in clinical trial NCT04297124 (A Study to Evaluate the Metabolism and Excretion of [14C]-CC-90009 in Healthy Male Subjects).

    Synonyms: 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1h-isoindol-5-yl)methyl)-2,2-difluoroacetamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  3. Drug

    Epinephrine

    go.drugbank.com/drugs/DB00668
    ApprovedInvestigationalVet approved

    On August 16, 2018, Teva Pharmaceuticals USA gained approval to market its generic epinephrine auto-injector in 0.3 mg and 0.15 mg strengths [L4353]. … It can be used in severe cases of croup [L4824].

    Synonyms: 4-((1R)-1-HYDROXY-2-(METHYLAMINO)ETHYL)-1,2-BENZENEDIOL, 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediolInternational brands: Epi EZ Pen JR
  4. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    In particular, it is generally proposed that the S-enantiomer is capable of eliciting stronger pharmacological activity than the R-enantiomer.[A39194] … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.

    Synonyms: (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid, (±)-2-(p-isobutylphenyl)propionic acidInternational brands: Act-3, Alges-X
  5. Drug

    Quinapril

    go.drugbank.com/drugs/DB00881
    ApprovedInvestigational

    [A184844] Quinapril was granted FDA approval on 19 November 1991.[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423] … [L8420,L8423] It is used to treat hypertension and heart failure.

    Mixtures: ACCUZIDE FORT 20 MG/25 MG FILM KAPLI TABLET, 30 ADET, ACCUZIDE 20 MG/12.5 MG FILM TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Ampicillin

    go.drugbank.com/drugs/DB00415
    ApprovedInvestigationalVet approved

    Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.

    Mixtures: BACTAMED 500 MG/250 MG IM IV ENJEKTABL TOZ IÇEREN FLAKON, 10 ADET, AZOSILIN 500 MG/50 MG TABLET, 12 ADETCategories: Penicillin G, Heterocyclic Compounds, 2-Ring
  7. Drug

    LPT-99

    go.drugbank.com/drugs/DB17142
    Experimental

    Synonyms: 2-(4-(2,4-dichlorophenethyl)-3,6-dioxo-1-(2-(thiophen-2-yl)ethyl)piperazin-2-yl)-n-(2-(5-methoxy-1h-indol-3-yl)ethyl) acetamide, 2-(4-(2,4-dichlorophenethyl)-3,6-dioxo-1-(2-(thiophen-2-yl)ethyl)piperazin-2-yl)-n-(2-(5-methoxy-1h-indol-3-yl)ethyl)acetamide
  8. Drug

    Rabeprazole

    go.drugbank.com/drugs/DB01129
    ApprovedInvestigational

    It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. … Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.

    Mixtures: RABEDIC 10/75 MG MR KAPSÜL, 20 ADET, RABEDIC 10/75 MG MR KAPSÜL, 30 ADETCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  9. Drug

    (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime

    go.drugbank.com/drugs/DB08553
    Experimental

    (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime is a solid. This compound belongs to the phenylpyrazoles. … These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group. It targets the protein serine/threonine-protein kinase B-raf.

    Synonyms: (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
  10. Drug

    Dexamethasone

    go.drugbank.com/drugs/DB01234
    ApprovedInvestigationalVet approved

    Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms

    Synonyms: 16α-Methyl-9α-fluoro-1-dehydrocortisol, 1-Dehydro-16α-methyl-9α-fluorohydrocortisoneMixtures: NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, VITATRIOL (NEOMICINA 3.5 MG + POLIMIXINA B SULFATO 6000 U.I. + DEXAMETASONA 1 MG)/1ML