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Eragidomide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Identification

Generic Name
Eragidomide
DrugBank Accession Number
DB19242
Background

Eragidomide is under investigation in clinical trial NCT04297124 (A Study to Evaluate the Metabolism and Excretion of [14C]-CC-90009 in Healthy Male Subjects).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 461.85
Monoisotopic: 461.0953901
Chemical Formula
C22H18ClF2N3O4
Synonyms
  • 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1h-isoindol-5-yl)methyl)-2,2-difluoroacetamide
External IDs
  • CC-90009
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
R76M2Z6366
CAS number
1860875-51-9
InChI Key
PWBHUSLMHZLGRN-UHFFFAOYSA-N
InChI
InChI=1S/C22H18ClF2N3O4/c23-15-4-2-14(3-5-15)22(24,25)21(32)26-10-12-1-6-16-13(9-12)11-28(20(16)31)17-7-8-18(29)27-19(17)30/h1-6,9,17H,7-8,10-11H2,(H,26,32)(H,27,29,30)
IUPAC Name
SMILES
FC(F)(C(=O)NCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O)C1=CC=C(Cl)C=C1

References

General References
Not Available
ChemSpider
88295982
ChEMBL
CHEMBL4742712

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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1CompletedTreatmentHealthy Volunteers (HV)1somestatusstop reasonjust information to hide
1TerminatedTreatmentAcute Myeloid Leukemia1somestatusstop reasonjust information to hide
1TerminatedTreatmentAcute Myeloid Leukemia / Myelodysplastic Syndrome1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at July 10, 2024 15:20 / Updated at July 11, 2024 07:56