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Displaying results 2181 - 2190 of 7018 in total
  1. Drug

    Papain

    go.drugbank.com/drugs/DB11193
    ApprovedWithdrawn

    Papain is also used as an ingredient in various enzymatic debriding preparations. … Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, _Carica papaya_ and _Vasconcellea cundinamarcensis_.

  2. Drug

    Evinacumab

    go.drugbank.com/drugs/DB15354
    ApprovedInvestigational

    was these observations that provided a rationale for the development of a therapy targeted against ANGPTL3. … Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein 3 (ANGPTL3) and the first drug of its kind.

  3. Drug

    Eftrenonacog alfa

    go.drugbank.com/drugs/DB11608
    Approved

    episodes caused spontaneously or as a result of accidental or surgical trauma [FDA Label]. … Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis.

  4. Drug

    Isopropamide

    go.drugbank.com/drugs/DB01625
    ApprovedVet approvedWithdrawn

    Isopropamide iodide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.

  5. Drug

    Guanabenz

    go.drugbank.com/drugs/DB00629
    ApprovedWithdrawn

    Guanabenz is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.

  6. Drug

    Cholestyramine

    go.drugbank.com/drugs/DB01432
    ApprovedInvestigational

    Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Phenoxypropazine

    go.drugbank.com/drugs/DB09251
    ApprovedWithdrawn

    It was marketed as an antidepressant in 1961 but was later withdrawn in 1966 because of its hepatotoxic potential. … Phenoxypropazine is a non-selective and irreversible monoamine oxidase enzyme inhibitor (MAOI), belonging to the _hydrazine_ chemical class.

  8. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme at … [A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion.

    Products: ESOMEPRAZOL - CT 20MG, ESOMEPRAZOL - CT 40MG
  9. Drug

    Tazobactam

    go.drugbank.com/drugs/DB01606
    ApprovedInvestigational

    It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections. … Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms.

    Mixtures: PIPTAZ-AFT POWDER FOR SOLUTION FOR INJECTION 4.5G/VIAL, KABICTAM® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE
  10. Drug

    Biropepimut-S

    go.drugbank.com/drugs/DB14816
    Investigational

    Biropepimut-S is under investigation in clinical trial NCT02873819 (Safety and Efficacy Study of GL-0817 (With Cyclophosphamide) for the Prevention of Recurrence of Squamous Cell Carcinoma of the Oral

    Synonyms: MAGE-A3 trojan peptide vaccine, LYS-VAL-ALA-GLU-LEU-VAL-HIS-PHE-LEU-ARG-VAL-LYS-ARG-PHE-LEU-TRP-GLY-PRO-ARG-ALA-LEU-VAL-ARG-VAL-LYS-ARG-VAL-ILE-PHE-SER-LYS-ALA-SER-SER-SER-LEU-GLN-LEU-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG