Search
Eladocagene exuparvovec
go.drugbank.com/drugs/DB16780ApprovedInvestigational[L43642] Eladocagene exuparvovec received EMA approval in July 2022. … [A253687] It was subsequently approved by the FDA in November 2024.[L51898,L51893]
Categories: Complex MixturesRituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalFDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of conditions [FDA label]. … On November 28, 2018, the US FDA approved _Truxima_, the first biosimilar to Rituxan (Rituximab) [L4808].
Latanoprostene bunod
go.drugbank.com/drugs/DB11660ApprovedConversely however, latanoprostene bunod integrates an NO-donating moiety in lieu of the isopropyl ester typically found in latanoprost. … In comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone.
Pyridostigmine
go.drugbank.com/drugs/DB00545ApprovedInvestigational[L32408, L32413] In addition to treating myasthenia gravis, pyridostigmine is used to reverse neuromuscular blocks, relieve symptoms in congenital myasthenic syndromes, and protect against certain nerve … By inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and relieve symptoms.
International brands: Kalymin NLycopene
go.drugbank.com/drugs/DB11231ApprovedTomato lycopene extract is used as a color additive in food products. … Lycopene is a naturally occurring red carotenoid pigment that is responsible for red to pink colors seen in tomatoes, pink grapefruit, and other foods [A27242].
Categories: Compounds used in a research, industrial, or household settingPrilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigationalCurrently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Mixtures: LIDOCAINA E PRILOCAINA TEVA, LIDOCAINA E PRILOCAINA TEVASynonyms: alpha-n-Propylamino-2-methylpropionanilide, N-(2-Methylphenyl)-2-(propylamino)propanamideBufexamac
go.drugbank.com/drugs/DB13346ApprovedWithdrawnIt has also been used in suppositories in combination with local anaesthetics indicated for haemorrhoids. … Bufexamac was also withdrawn by the EMA in April 2010.
Synonyms: 4-Butoxy-N-hydroxybenzeneacetamideRurioctocog alfa pegol
go.drugbank.com/drugs/DB16007ApprovedInvestigationalIt was first approved by the European Commission in January 2018. … Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous
Netarsudil
go.drugbank.com/drugs/DB13931ApprovedInvestigationalhumour outflow to act as an inhibitor to the rho kinase and norepinephrine transporters found there as opposed to affecting protaglandin F2-alpha analog like mechanisms in the unconventional uveoscleral … production of aqueous As of December 18, 2017 the FDA approved Aerie Pharmaceutical's Rhopressa (netarsudil ophthalmic solution) 0.02% for the indication of reducing elevated intraocular pressure in
Vinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalIt was first described in 1998 at the Pierre Fabre research center in France. … Vinflunine ditartrate is an active ingredient in the EMA-authorised product Javlor for intravenous infusion.