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Displaying results 211 - 220 of 10000 in total
  1. Drug

    Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

    go.drugbank.com/drugs/DB16757
    Approved

    [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with the AS03 adjuvant system prior to administration. … [L40694] While the concept of plant-based VLPs as vaccines is not new,[A245824] it is a novel approach to COVID-19 vaccination, with previously approved COVID-19 vaccines mostly comprising viral vector

    Synonyms: Recombinant SARS-CoV-2 spike (S)-protein virus-like particle
  2. Drug

    Dexrazoxane

    go.drugbank.com/drugs/DB00380
    ApprovedInvestigationalWithdrawn

    It appears to inhibit formation of a toxic iron-anthracycline complex. … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy.

    Synonyms: (+)-(S)-4,4'-Propylenedi-2,6-piperazinedione, 2,6-Piperazinedione, 4, 4'-(1-methyl-1,2-ethanediyl)bis-, (S)- (9CI)Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  3. Drug

    Azacitidine

    go.drugbank.com/drugs/DB00928
    ApprovedInvestigational

    One of them is the induction of cytotoxicity. As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis. … Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one, 5 Azacitidine
  4. Drug

    (E)-(S)-4-[(S)-4-METHYL-2-((S)-3-METHYL-2{(S)-2-[(5-METHYL-ISOXAZOLE-3- CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-PENTANOYLAMINO]-5-((S)-2- OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID ETHYL ESTER

    go.drugbank.com/drugs/DB04710
    Experimental

    Synonyms: (E)-(S)-4-[(S)-4-METHYL-2-((S)-3-METHYL-2{(S)-2-[(5-METHYL-ISOXAZOLE-3- CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-PENTANOYLAMINO]-5-((S)-2- OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID ETHYL ESTER
  5. Drug

    ISA101b

    go.drugbank.com/drugs/DB18694
    Investigational

    ISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins.

    Synonyms: Peltopepimut-S
  6. Drug

    (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID

    go.drugbank.com/drugs/DB08161
    Experimental

    Synonyms: (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID
  7. Drug

    Carboprost tromethamine

    go.drugbank.com/drugs/DB00429
    ApprovedInvestigational

    A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.

    Synonyms: 15(S)-15-methyl-PGF2α tromethamine salt, 15(S)-15-methylprostaglandin F2α tromethamineCategories: Prostaglandins F, Synthetic
  8. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension.

    Mixtures: COSOPT S 20/5MG/ML, COSOPT S 20MG/ML+5MG/MLCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  9. Drug

    Asparagine

    go.drugbank.com/drugs/DB00174
    ApprovedNutraceuticalWithdrawn

    A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase.

    Mixtures: AMINOPLASMAL-5% E INFUSION, AMINOPLASMAL-10% E INFUSIONSynonyms: (S)-Asparagine, (S)-2-amino-3-carbamoylpropanoic acid
  10. Drug

    DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID

    go.drugbank.com/drugs/DB04585
    Experimental

    Synonyms: DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID