Carboprost tromethamine is a prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective. A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
- Mechanism
- Curator reviewed
Carboprost is a synthetic prostaglandin. It binds the prostaglandin E2 receptor, causing myometrial contractions, casuing the induction of labour or the expulsion of the placenta. Prostaglandins occur naturally in the body and act at several sites in the body including the womb (uterus). They act on the muscles of the womb, causing them to contract.
- Primary indication
- For aborting pregnancy between the 13th and 20th weeks of gestation as calculated from the first day of the last normal menstrual period and in the following conditions related to second trimester abortion: 1.Curator reviewed · 2 structured indications
- Formula / weight
- C25H47NO8 · 489.65 g/mol (avg)
- First approval
- Canada, 2003 · United States, 1979
- Also known as
- Carboprost trometamol
- Code names
- U 32921 E
- Brand names
Resolves to
UMMADZJLZAPZAW-XOWPVRJPSA-NSMILESNC(CO)(CO)CO.CCCCC[C@](C)(O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=OWhat you can answer from here — as of August 31, 2026
Which drugs share a target with Carboprost tromethamine, and which of those have an active Phase 3 trial?
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