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Dabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigationalDabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor [dabigatran].
Products: Dabigatran G.L. 75 mg-Hartkapseln, Dabigatran G.L. 110 mg-HartkapselnMupirocin
go.drugbank.com/drugs/DB00410ApprovedInvestigationalVet approveda therapeutic advantage. … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents.
Synonyms: Pseudomonic acid AInternational brands: T-BactIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigationalIt was the first available over-the-counter NSAID.[A39076] On the available products, ibuprofen is administered as a racemic mixture. … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.
Mixtures: Rx Act Ibuprofen PM, PAX MAX GEL®International brands: Act-3Sunitinib
go.drugbank.com/drugs/DB01268ApprovedInvestigationalFor these purposes, sunitinib is generally available as an orally administered formulation. Sunitinib inhibits cellular signaling by targeting multiple RTKs. … Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic IndexProducts: Nat-sunitinib, Sunitinib G.L. 25 mg-HartkapselnPomalidomide
go.drugbank.com/drugs/DB08910ApprovedInvestigationalPomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: Nat-pomalidomide, Pomalidomid G.L. 1 mg-HartkapselnRefractory to at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti‐CD38 monoclonal antibody
go.drugbank.com/conditions/DBCOND0121033Drugs: SelinexorSynonyms: Refractory to at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti‐CD38 monoclonal antibodyCentella asiatica
go.drugbank.com/drugs/DB14256ApprovedCentella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Ato Standard Intensivecream, Ato Standard Premium MildcreamProducts: GZE Watery Sun Gel, Centellaca A Clear Relaxing TonerTravoprost
go.drugbank.com/drugs/DB00287ApprovedInvestigational[L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher efficacy in reducing intraocular pressure and a reduced … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist.
Mixtures: TRAVO/TIMOL AL 40UG/ML+5MG, TRAVO/TIMOL AL 40UG/ML+5MGProducts: TRAVATAN 40UG ATR, TRAVATAN 40UG/ML ATRAtorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigationalPrescribing statins is considered standard practice for patients following any cardiovascular event, and for people who are at moderate to high risk of developing cardiovascular disease. … [T568] It is a pentasubstituted pyrrole [A177415] formed by two contrasting moieties with an achiral heterocyclic core unit and a 3,5-dihydroxypentanoyl side chain identical to its parent compound.
Mixtures: TIAZOMET ® A 40/10 TABLETASProducts: Atorvastatin G.L. 10 mg - Filmtabletten, Atorvastatin G.L. 20 mg - FilmtablettenPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigationalmedications, which also includes [rosiglitazone] and [troglitazone], exerts its pharmacological effect primarily by promoting insulin sensitivity and the improved uptake of blood glucose[L11416] via agonism at … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.
Products: Ag-pioglitazone, Pioglitazon G.L. 15 mg - Tabletten