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Displaying results 2191 - 2200 of 10000 in total
  1. Drug

    Calcium Phosphate

    go.drugbank.com/drugs/DB11348
    ApprovedInvestigational

    Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] [L851].

    Mixtures: Milk Calcium With Vitamins C, D, and Phosphorous, Milk Calcium With Vitamins C, D, and PhosphorousCategories: Compounds used in a research, industrial, or household setting, ascorbic acid (vit C) and calcium
  2. Drug

    Doxecitine

    go.drugbank.com/drugs/DB02594
    ApprovedInvestigational

    It is an essential component of the deoxyribonucleotide pool required for DNA synthesis and repair. … Doxecitine is a synthetic form of the naturally occurring pyrimidine deoxyribonucleoside deoxycytidine.

    Synonyms: 1-(2-Deoxy-β-D-ribofuranosyl)cytosine, 1-(2-deoxy-.beta.-d-ribofuranosyl)cytosineCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Amsacrine

    go.drugbank.com/drugs/DB00276
    ApprovedInvestigationalWithdrawn

    It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. … Aminoacridine derivative that is a potent intercalating antineoplastic agent.

    Synonyms: 4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide, 4'-(9-Acridinylamino)methanesulfon-m-anisidideInternational brands: AMSA P-D
  4. Drug

    Ancestim

    go.drugbank.com/drugs/DB09103
    ApprovedWithdrawn

    [T68] It was also approved by Health Canada in 1999 but it is currently under the status of canceled post-market.[L1087] … Ancestim was developed by Amgen and sold to Biovitrium in December 2008. It was submitted to the FDA under the status of recommendation for approval with a 10 to 1 votes.

  5. Drug

    Chondroitin sulfate

    go.drugbank.com/drugs/DB09301
    ApprovedInvestigationalNutraceutical

    Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine and 1,4-β-d-glucuronic acid units which bear 4-O- and/or 6-O-sulfations at the N-acetylgalactosamine units disposed of in specific … [A32063] Chondroitin sulfate is sold as an OTC dietary supplement in North America and it is a prescription drug under the EMA in Europe.[A32066]

    Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: Nn Bio Chondroitin 400, Kordel"s Chondroitin 400mg
  6. Target

    Antigen peptide transporter 1

    go.drugbank.com/bio_entities/BE0003109
    TransporterHumans

    In complex with TAP2 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules (PubMed:25377891, PubMed:25656091

    Synonyms: Peptide transporter involved in antigen processing 1
  7. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … In depressed individuals, desipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.

    Synonyms: N-(3-methylaminopropyl)iminobibenzyl, DMICategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Combined Inhibitors of Serotonin/Norepinephrine Reuptake
  8. Drug

    Sodium zirconium cyclosilicate

    go.drugbank.com/drugs/DB14048
    ApprovedInvestigational

    the median time to achieving normal potassium levels in the blood was 2.2 hours, with 92% of patients achieving normal potassium levels within 48 hours following administration. … [L2933] Approval of the medication is supported by data from three double-blind, placebo-controlled trials and two open-label trials which showed that the onset of action was approximately 1.0 hour and

    Categories: Compounds used in a research, industrial, or household setting, Ion Exchange ResinsProducts: SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET, SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 11 ADET
  9. Drug

    Tasosartan

    go.drugbank.com/drugs/DB01349
    Experimental

    Tasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan. … It is used to treat patients with essential hypertension.

    Categories: Angiotensin II receptor blockers (ARBs), plain, Agents Acting on the Renin-Angiotensin System
  10. Drug

    Ublituximab

    go.drugbank.com/drugs/DB11850
    ApprovedInvestigational

    [A244210] Ublituximab is a chimeric anti-CD20 IgG1κ antibody produced in the rat YB2/0 cell line to target a unique epitope and enhance ADCC compared to other approved anti-CD20 antibodies such as [rituximab … CD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers and autoimmune conditions.

    Categories: Leukemia, Lymphocytic, Chronic, B-Cell, drug therapy