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Displaying results 2201 - 2210 of 10000 in total
  1. Target

    3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase

    go.drugbank.com/bio_entities/BE0001679
    TargetMycobacterium tuberculosis

    Probably involved in steroid metabolism. Catalyzes the oxidation of androsterone (3alpha-hydroxy-5alpha-androstan-17-one) and 20beta-hydroxyprogesterone (4-pregnen-20beta-ol-3-one), and the reduction of progesterone (4-pregnen-3,20-dione...

    Polypeptides: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
  2. Target

    tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

    go.drugbank.com/bio_entities/BE0020091
    EnzymeHumans

    Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704, PubMed:34798057, PubMed:38680565). Specifically modifies U20 in cytoplasmic ...

    Polypeptides: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
  3. Drug

    Pramocaine

    go.drugbank.com/drugs/DB09345
    Approved

    Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison i...

    Mixtures: DG Health Antibiotic, DG Health AntibioticProducts: Ear Itch MD
  4. Target

    Chain A, Red Copper Protein Nitrosocyanin

    go.drugbank.com/bio_entities/BE0002711
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Chain A, Red Copper Protein Nitrosocyanin
  5. Target

    Cytochrome b6-f complex subunit 7

    go.drugbank.com/bio_entities/BE0003908
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex subunit 7Synonyms: Cytochrome b6-f complex subunit PetM, Cytochrome b6-f complex subunit VII
  6. Target

    Cytochrome b6-f complex subunit 8

    go.drugbank.com/bio_entities/BE0003909
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex subunit 8Synonyms: Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII
  7. Target

    Trafficking protein particle complex subunit 6A

    go.drugbank.com/bio_entities/BE0004275
    TargetHumans

    May play a role in vesicular transport during the biogenesis of melanosomes

    Polypeptides: Trafficking protein particle complex subunit 6ASynonyms: TRAPP complex subunit 6A
  8. Target

    Trafficking protein particle complex subunit 5

    go.drugbank.com/bio_entities/BE0004277
    TargetHumans

    May play a role in vesicular transport from endoplasmic reticulum to Golgi

    Polypeptides: Trafficking protein particle complex subunit 5
  9. Target

    Nuclear factor NF-kappa-B complex

    go.drugbank.com/bio_entities/BE0009554
    TargetHumans

    The heterodimeric RELA-NFKB1 complex appears to be most abundant one. … NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to

  10. Drug

    Obeticholic acid

    go.drugbank.com/drugs/DB05990
    ApprovedInvestigational

    The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected to be granted full approval for this indication in 2020.[L12636]