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Displaying results 2201 - 2210 of 10000 in total
  1. Drug

    Golimumab

    go.drugbank.com/drugs/DB06674
    ApprovedInvestigational

    treatment in patients with active psoriatic arthritis (PsA), (iii) as a single agent in patients with active ankylosing spondylitis (AS), and (iv) as a single agent in patients with moderate to severe … Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate

    Products: Simponi Solution for Injection in Pre-filled Syringe 50 mg/0.5 ml, Solution for Injection in Pre-filled Syringe 100 mg/1.0 ml
  2. Drug

    1,3-bis-([3-[3-[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino-3,4-dioxo-cyclobutenyl]-amino-propoxy-ethoxy-ethoxy]-propyl-]amino-carbonyloxy)-2-amino-propane

    go.drugbank.com/drugs/DB02572
    Experimental

    Synonyms: 1,3-bis-([3-[3-[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino-3,4-dioxo-cyclobutenyl]-amino-propoxy-ethoxy-ethoxy]-propyl-]amino-carbonyloxy)-2-amino-propane
  3. Drug

    Velmupressin

    go.drugbank.com/drugs/DB18783
    Investigational

    Synonyms: L-prolinamide, 4-chloro-n-(4-mercapto-1-oxobutyl)-l-phenylalanyl-3-(2-thienyl)-l-alanyl-l-valyl-l-asparaginyl-l-cysteinyl-n-(4-((aminoiminomethyl)amino)butyl)-, cyclic (1->5)-thioether
  4. Drug

    Erythropoietin

    go.drugbank.com/drugs/DB00016
    ApprovedInvestigational

    Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. … Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant DNA technology and is used for the treatment of patients with anemia associated with

    Synonyms: 1-165-Erythropoietin (human clone λHEPOFL13 protein moiety), glycoform αProducts: EPORON 2000 IU/0,5 ML KULLANIMA HAZIR 5 ENJEKTOR, EPORON 4000 IU/0,4 ML KULLANIMA HAZIR 5 ENJEKTOR
  5. Drug

    Duvoglustat

    go.drugbank.com/drugs/DB03206
    Investigational

    An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-amino-1,5-dideoxy-D-glucopyranose, D-1-deoxynojirimycin
  6. Drug

    4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-Fluoro-Phenyl)-3-(3-Chloro-2-Fluoro-Phenyl)-4-Cyano-5-(2,2-Dimethyl-Propyl)-Pyrrolidine-2-Carbonyl]-Amino}-3-Methoxy-Benzoic Acid

    go.drugbank.com/drugs/DB17388
    Experimental

    Synonyms: 4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-Fluoro-Phenyl)-3-(3-Chloro-2-Fluoro-Phenyl)-4-Cyano-5-(2,2-Dimethyl-Propyl)-Pyrrolidine-2-Carbonyl]-Amino}-3-Methoxy-Benzoic Acid
  7. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … [A188826,A188832] Clinicians are advised to initiate therapeutic drug monitoring in patients who require phenytoin since even small deviations from the recommended therapeutic range can lead to suboptimal

    Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapCategories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  8. Drug

    [1-(3-hydroxy-2-oxo-1-phenethyl-propylcarbamoyl)2-phenyl-ethyl]-carbamic acid pyridin-4-ylmethyl ester

    go.drugbank.com/drugs/DB02128
    Experimental

    Synonyms: N-[(3S)-1-hydroxy-2-oxo-5-phenyl-3-pentanyl]-Nα-[(3-pyridinylmethoxy)carbonyl]-L-phenylalaninamide, [1-(3-hydroxy-2-oxo-1-phenethyl-propylcarbamoyl)2-phenyl-ethyl]-carbamic acid pyridin-4-ylmethyl ester
  9. Drug

    Zoledronic acid

    go.drugbank.com/drugs/DB00399
    ApprovedInvestigational

    [L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994.[A203120] Zoledronic acid was granted FDA approval on 20 August 2001.[L13712] … Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid].

    Salts: Zoledronate D,L-Lysine MonohydrateCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Calcimycin

    go.drugbank.com/drugs/DB19408
    Investigational

    Primarily used as a biochemical tool for studying divalent cations in biological systems, Calcimycin also exhibits antibiotic activity against gram-positive bacteria and fungi. … It binds to and transports calcium and other divalent cations across membranes, disrupts oxidative phosphorylation, and inhibits ATPase in rat liver mitochondria.

    Synonyms: 4-benzoxazolecarboxylic acid, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-4-benzoxazolecarboxylic acidCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-Ring