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Ginsenoside Rb1
go.drugbank.com/drugs/DB06749ExperimentalNutraceuticalRecent research shows that Rb1 affects rat embryo development and has teratogenic effects, causing birth defects.
Tazemetostat
go.drugbank.com/drugs/DB12887ApprovedInvestigationalTazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
Dotatate gallium Ga-68
go.drugbank.com/drugs/DB13925ApprovedInvestigationalWithdrawnGa-68 dotatate has a high affinity for somatostatin-2 receptor and it is rapidly excreted from the nontarget sites which gives it an ideal candidate for imaging neuroendocrine tumors. … Dotatate gallium (Ga-68) is a somatostatin-2 receptor analog which is radiolabeled with gallium 68 as a positron-emitting radioisotope.
Formestane
go.drugbank.com/drugs/DB08905ApprovedWithdrawnIt is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes. … Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
Rilpivirine
go.drugbank.com/drugs/DB08864ApprovedInvestigational[L31193] While previously administered once-monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in … Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients.[A31328] It is a diarylpyrimidine derivative.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseClobetasol propionate
go.drugbank.com/drugs/DB01013ApprovedInvestigationalClobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.
Miocamycin
go.drugbank.com/drugs/DB13287ApprovedThis drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia [L5737].
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseIsoniazid
go.drugbank.com/drugs/DB00951ApprovedInvestigationalIt remains the treatment of choice for tuberculosis.
Categories: Antiinfectives for Systemic Use, Drugs for Treatment of TuberculosisPerboric acid
go.drugbank.com/drugs/DB13235Approved[L1113] By the FDA, sodium perborate is approved as an ointment for the protection of poison ivy dermatitis.[L2764]
Categories: Antiinfectives and Antiseptics for Local Oral TreatmentUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceuticalIt is fundamental for cells that have a high metabolic demand. … [A31413] The ubidecarenone is the coenzyme destined for mitochondrial enzyme complexes involved in oxidative phosphorylation in the production of ATP.