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Displaying results 2231 - 2240 of 10000 in total
  1. Drug

    Bosentan

    go.drugbank.com/drugs/DB00559
    ApprovedInvestigational

    Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure. … Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals.

    Categories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and AntisepticsSynonyms: 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide, p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
  2. Drug

    CTX120

    go.drugbank.com/drugs/DB18625
    Investigational

    CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.

    Synonyms: allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting B-cell maturation antigen
  3. Indication

    Relapsed Multiple Myeloma

    go.drugbank.com/conditions/DBCOND0031510
    Drugs: Belantamab mafodotin · Carfilzomib · Ciltacabtagene autoleucel · Daratumumab · Dexamethasone · Elranatamab +8 more
    Synonyms: Multiple Myeloma in Relapse
  4. Drug

    Lecithin, soybean

    go.drugbank.com/drugs/DB14161
    Investigational

    The emulsifying and surfactant properties are useful in food additives and for forming organogels (gels). … Lecithin is a component of the cell membrane and commercially extracted from soybeans and egg yolk.

    Products: Essentiale Forte N, VitaHealth Lecithin 1200mg
  5. Drug

    Lactobacillus fermentum

    go.drugbank.com/drugs/DB16542
    Investigational

    Products: Pharmanex ProBio PCC Capsule 100mg
  6. Indication

    Keratoconjunctivitis Sicca (KCS)

    go.drugbank.com/conditions/DBCOND0105777
    Drugs: Hydroxypropyl cellulose
    Synonyms: Keratoconjunctivitis sicca, in Sjögren syndrome, Keratoconjunctivitis sicca, in Sjogren's syndrome
  7. Indication

    Felty's Syndrome

    go.drugbank.com/conditions/DBCOND0076051
    Drugs: Sodium aurothiomalate
    Synonyms: Rheumatoid arthritis, leucopenia AND splenomegaly, Rheumatoid arthritis, leukopenia AND splenomegaly
  8. Drug

    Nicorandil

    go.drugbank.com/drugs/DB09220
    ApprovedInvestigationalWithdrawn

    Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. … It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium channels.

    Categories: Vasodilators Used in Cardiac DiseasesSynonyms: N-(2-Hydroxyethyl)nicotinamide nitrate, N-(2-Hydroxyethyl)nicotinamide nitrate (ester)
  9. Drug

    Exametazime

    go.drugbank.com/drugs/DB11179
    Approved

    It is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous leukocytes. … It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex.

    Products: CERETEC TM INJ (SINGLE DOSE UNIT)
  10. Drug

    Lofexidine

    go.drugbank.com/drugs/DB04948
    ApprovedInvestigational

    [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018.[L2794] … [A33084] It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment of hypertension than clonidine.

    Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive Disorders