NCT03418259
Intra-Nasal Mechanical Stimulation (INMEST) as a Treatment of Keratoconjunctivitis Sicca (Dry Eye Syndrome) No drug interventions treatment Not Available completed NCT05848128
Efficacy and Safety Evaluation of Tavilermide Ophthalmic Solution for the Treatment of Dry Eye treatment 3 completed NCT03652415
DRy Eye Outcome and Prescription Study No drug interventions Not Available Not Available unknown_status NCT05825352
PMCF Study to Evaluate Performance and Safety of "Ocular Drops Based Upon Carmellose" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT03616899
Safety and Efficacy of KPI-121 in Subjects With DED treatment 3 completed NCT05825586
PMCF Study to Evaluate Performance and Safety of "Distilled Waters-based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT05119920
Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease treatment 2 completed NCT06329687
A Study Evaluating the Safety of the Nasal Pump treatment 4 terminated NCT06176651
Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers treatment 4 completed NCT05823961
PMCF Study to Evaluate Performance and Safety of "CLHA-based Eyedrops" Used to Improve Lacrimal Abnormalities No drug interventions treatment Not Available completed NCT03878628
Treatment With Allogeneic Adipose-derived Mesenchymal Stem Cells in Patients With Aqueous Deficient Dry Eye Disease No drug interventions treatment 0 completed NCT05825599
PMCF Study to Evaluate Performance and Safety of "HPMC-based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT05807360
PMCF Study to Evaluate Performance and Safety of "Hyaluronic Acid (HA)-Based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT00407043
Multicenter, Randomized, Controlled Study of the Effect of Lotemax on Initiation of Dry Eye Treatment With Restasis treatment 4 completed NCT04649177
Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting No drug interventions treatment Not Available completed NCT01057147
Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Subjects With Dry Eye - Effects on Central Cornea treatment 2 completed NCT00128245
Safety and Efficacy of Pimecrolimus Ophthalmic Suspension in Patients With Moderate to Severe Keratoconjunctivitis Sicca treatment 2 completed NCT01421498
Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1) treatment 3 completed NCT00848198
TearLab Core Validation Study to Establish Referent Values for Dry Eye Disease No drug interventions Not Available Not Available completed NCT04421300
A Randomized Study of Smile Exercise for Dry Eye treatment Not Available completed NCT02970799
Tear Production by Nasal Neurostimulation Compared to Active Control No drug interventions other Not Available completed NCT05918406
Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya No drug interventions treatment 4 completed NCT01027013
Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Patients With Dry Eye treatment 2 completed NCT00025818
Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome treatment 3 completed NCT01235234
Trial of CF101 to Treat Patients With Dry Eye Disease treatment 3 completed NCT02665234
A Safety and Efficacy Study of Tavilermide (MIM-D3) Ophthalmic Solution for the Treatment of Dry Eye Disease treatment 3 completed NCT01797822
Effects of Dry Eye Treatments on the Ocular Surface treatment 4 completed NCT05618730
Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort B No drug interventions treatment 1 active_not_recruiting NCT00349466
Safety and Efficacy Study of CF101 to Treat Keratoconjunctivitis Sicca treatment 2 completed NCT02254265
Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca No drug interventions treatment 2 / 3 completed NCT00681265
Tear Film Break-up Time After Instillation of Artificial Tears treatment Not Available completed NCT02845674
An Open-Label Extension of a Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis Sicca No drug interventions treatment 3 completed NCT00411827
Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK No drug interventions treatment Not Available unknown_status NCT03925727
Tavilermide Ophthalmic Solution for the Treatment of Dry Eye treatment 3 completed NCT03436576
Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eye treatment 3 unknown_status NCT02188160
Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease treatment 2 completed NCT01226680
A Study Of Tasocitinib In Dry Eye Subjects treatment 2 withdrawn NCT02798289
Acute Tear Production Following Single Use of the Oculeve Intranasal Neurostimulator No drug interventions supportive_care Not Available completed NCT02121301
A Clinical Study to Assess the Safety and Efficacy of an Ophthalmic Solution (SkQ1) in the Treatment of Dry Eye Syndrome (DES) treatment 2 completed NCT00201981
Study of Rebamipide Eye Drops to Treat Dry Eye treatment 3 completed NCT00201955
Study of Rebamipide Eye Drops to Treat Dry Eye treatment 3 completed NCT03706443
Tear Lipid Layer Thickness Changes With Use of Emollient and Non-Emollient Eye Drops No drug interventions treatment Not Available completed NCT00426543
Effect of B-cell Depletion in Patients With Primary Sjögren's Syndrome treatment 2 completed NCT03953703
Levocarnitine for Dry Eye in Sjogren's Syndrome treatment 2 recruiting NCT02526290
Six Month Study to Evaluate the Safety and Effectiveness of the Intranasal Lacrimal Neurostimulator No drug interventions supportive_care Not Available completed NCT02819284
Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye Disease treatment 3 completed NCT00554879
Acupuncture Treatment of Dry Eye No drug interventions treatment Not Available completed NCT02117687
A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry Eye treatment 4 completed NCT02139033
A Phase 4 Study Investigating the Efficacy of Retaine™ in Managing Signs and Symptoms Associated With Dry Eye Syndrome No drug interventions treatment 4 completed NCT02634853
A Safety and Efficacy Study of Tavilermide (MIM-D3) Ophthalmic Solution for the Treatment of Dry Eye treatment 3 completed NCT00037661
Study of INS365 Ophthalmic Solution in a Controlled Adverse Environment in Patients With Dry Eye treatment 3 completed NCT03753893
Ocular Manifestations in Rheumatic Diseases No drug interventions Not Available Not Available completed NCT02688556
Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis Sicca treatment 3 completed NCT03408015
Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease basic_science 4 withdrawn NCT01213342
Omega-3 Fatty Acid Supplements and Dry Eye No drug interventions treatment Not Available terminated NCT01900249
To Assess the Safety and Efficacy of R932348 Ophthalmic Solutions in Patients With Keratoconjunctivitis Sicca No drug interventions treatment 2 completed NCT00883649
Efficacy and Safety Study of Nutritional Supplements for Treatments of Dry Eye No drug interventions treatment Not Available completed NCT01547936
Effect of Controlled Adverse Environment (CAE) on Tear Film Stability No drug interventions Not Available Not Available completed NCT03398018
Repository Corticotropin Injection in Keratoconjunctivitis Sicca treatment 4 withdrawn NCT00717418
Efficacy Study of Cyclosporine Ophthalmic Emulsion in Patients With Dry Eye Disease Not Available Not Available completed NCT00345241
Effects of Systane Versus Saline in Maintaining Tear Film Stability at Determined Time Points treatment Not Available completed NCT04884217
Treatment of Dry Eye Disease Using Pro-ocular™ - A Proof of Concept, Safety, and Efficacy Study No drug interventions treatment 2 unknown_status NCT00851734
A Dose-Escalation Study to Assess the Safety and Tolerability of LX214 Ophthalmic Solution in Healthy Volunteers, Followed by an Open-Label Evaluation of LX214 in Patients With Keratoconjunctivitis Sicca (KCS) treatment 1 completed NCT02066896
Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome No drug interventions treatment Not Available completed NCT04493658
Differential Diagnosis of Sjögren's Versus Non-Sjögren's Dry Eye No drug interventions Not Available Not Available completed NCT02680158
A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome No drug interventions supportive_care Not Available completed NCT01102257
Dry Eye Assessment and Management: Feasibility Study treatment 2 / 3 completed NCT02813265
Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease treatment 3 completed NCT01817582
Lotemax® Gel 0.5% and Restasis 0.05% in Participants With Mild or Moderate Keratoconjunctivitis Sicca (Dry Eye Disease) treatment 2 completed NCT00001731
Treatment of Dry Eye Syndrome With Cyclosporin A Eye Drops treatment 2 completed NCT00987727
Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry Eye treatment 4 completed NCT00788229
Efficacy and Safety Study of ATs in Patients With Dry Eye Syndrome No drug interventions treatment 2 completed NCT01733992
A Safety, Tolerability and Pharmacokinetics Study of R932348 Eye Drops in Patients With Dry Eye Disease No drug interventions treatment 1 completed NCT04147650
Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye Syndrome treatment 2 / 3 completed