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Cisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnThe FDA issued a warning letter regarding this risk to health care professionals and patients. … In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: DISPEPRID 5 MG TABLET, 30 ADET, DISPEPRID 10 MG TABLET, 50 ADETAlendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalIt functions by preventing resorption of bone[FDA Label][A959]. … Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Mixtures: BONYL 70 MG/2800 IU TABLET, 12 ADET, BONMEGA 70 MG/2800 IU+1000 MG TEDAVI PAKETI, 4+24 ADETSynonyms: 4-amino-1-hydroxybutane-1,1-diphosphonic acid, (4-amino-1-hydroxybutylidene)bisphosphonic acidGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity … Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963.
International brands: G-Mycin, U-gencinMixtures: INDOBIOTIC GOZ DAMLASI, 5 ML, BELOGENT %0,05+%0,1 KREM, 15 GDesmopressin
go.drugbank.com/drugs/DB00035ApprovedInvestigationalIt was designed through two primary chemical modifications of the natural hormone: the deamination of 1-cysteine and the substitution of L-arginine with D-arginine at the 8th position [A31661, A275458] … On January 15, 2026, the FDA approved a new low-dose sublingual film formulation specifically for the treatment of nocturia in patients at high risk for fluid overload, utilizing a specialized delivery
Synonyms: 1 deamino 8 D argininevasopressin, 1-deamino-8-D-arginine vasopressinProducts: MINIRIN 4 MCG/ML 10 AMPUL, MINIRIN NASAL SPRAY 10 mcg/doseDapagliflozin
go.drugbank.com/drugs/DB06292ApprovedInvestigationalDapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. … [L48251] It was later approved to reduce the risk of kidney function decline, kidney failure, cardiovascular death, and hospitalization for heart failure in adults with chronic kidney disease in April
Mixtures: Qtern 5 mg/10 mg Film-Coated Tablets, QTERN 5 MG/10 MG FİLM KAPLI TABLET, 28 ADETCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: L-DeprenalinBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: CİBADREX 10/12,5 MG FİLM TABLET, 28 ADET, CİBADREX 5/6,25 MG FİLM TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-RingSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid and is
Mixtures: ZETIROL S ® 10/10 MG, ZINTREPID® TABLETAS 10 MG/10 MGCategories: P-glycoprotein inhibitors, P-glycoprotein substratesToyocamycin
go.drugbank.com/drugs/DB13916Experimental4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. … It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
Synonyms: 4-amino-5-cyano-7-(D-ribofuranosyl)-7H-pyrrolo(2,3-d)pyrimidine, 7-deaza-7-cyanoadenosineValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigational[A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … It is currently a compound of interest in the field of oncology for its anti-proliferative effects and is the subject of many clinical trials in a variety of cancer types.
Synonyms: 2-n-propyl-n-valeric acid, n-DPAMixtures: PROKSIVAL XR 300 MG UZUN ETKILI FILM TABLET, 50 ADET, PROKSIVAL XR 300 MG UZUN ETKILI FILM TABLET, 50 ADET