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Displaying results 2231 - 2240 of 10000 in total
  1. Drug

    Enmetazobactam

    go.drugbank.com/drugs/DB18716
    ApprovedInvestigational

    Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. … [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA on February 23, 2024, for the treatment of complicated urinary tract infections.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2E1 InhibitorsSynonyms: (2s,3s,5r)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-3-yl)methyl)-1-methyl-, inner salt
  2. Drug

    Ilomastat

    go.drugbank.com/drugs/DB02255
    Experimental

    Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (S-(R*,S*))-N(SUP 4)-HYDROXY-N(SUP 1)-(1H-INDOL-3-YLMETHYL)-2-(METHYLAMINO)-2-OXOETHYL)-2-(2-METHYLOPROPYL)BUTANEDIAMIDE, (R)-N(SUP 1)-HYDROXY-N-((S)-2-INDOL-3-YL-1-(METHYLCARBAMOYL)ETHYL)-2-ISOBUTYLSUCCINAMIDE
  3. Drug

    t-Butylhydroquinone

    go.drugbank.com/drugs/DB07726
    Experimental

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-t-Butylhydroquinone, 2-t-Butyl-1,4-benzenediol
  4. Drug

    Pipequaline

    go.drugbank.com/drugs/DB13991
    Experimental

    However, it presents a significant set of anxiolytic properties with a very little sedative, amnestic or anticonvulsant effect. … Due to these differences, this drug is classified as a nonbenzodiazepine anxiolytic.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-Phenyl-4-(2-(4-piperidyl)ethyl)quinoline
  5. Drug

    Picolinic acid

    go.drugbank.com/drugs/DB05483
    Experimental

    It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. … PCL-016 plays a key role in zinc transport.

    Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingSynonyms: 2-Carboxypyridine
  6. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated

    Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: YARDIX® 120 MG, DIFUMY-MS®240 MG CÁPSULAS DURA
  7. Drug

    Chlorophetanol

    go.drugbank.com/drugs/DB11368
    Experimental

    Chlorophetanol is an agent known to have antifungal activities.

    Synonyms: 2-(4-Chlorophenoxy)ethanol, 2-(4-chlorphenoxy)-ethanolCategories: 2-(4-chlorphenoxy)-ethanol
  8. Drug

    ABSK-012

    go.drugbank.com/drugs/DB18035
    Experimental

    Synonyms: 3-(5-cyano-4-(cyclopropylamino)pyridin-2-yl)-1-(6-formyl-5-((4-methyl-2-oxopiperazin-1-yl)methyl)pyridin-2-yl)-1-methylurea, N′-[5-Cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl]-2-pyridinyl]-N-methylurea
  9. Drug

    Methyl red

    go.drugbank.com/drugs/DB08209
    Experimental

    Synonyms: Acid Red 2, 2-((4-Dimethylamino)phenylazo)benzoic acidCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Bimiralisib

    go.drugbank.com/drugs/DB14846
    Investigational

    Bimiralisib is under investigation in clinical trial NCT02723877 (PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)).

    Synonyms: 2-Pyridinamine, 5-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)-, 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine