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Hydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigationalHydroxyzine is a first-generation histamine H<sub>1</sub>-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus
Products: Nu-hydroxyzine, AA PHARMA HYDROXYZINE CAPSULE 10 mgChenodeoxycholic acid
go.drugbank.com/drugs/DB06777ApprovedInvestigationalChenodeoxycholic acid is a bile acid naturally found in the body.
Pentetic acid
go.drugbank.com/drugs/DB14007ApprovedInvestigational[A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive ingredients for drug products by the FDA. … Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable
Categories: Compounds used in a research, industrial, or household settingSynonyms: DTP-AEvinacumab
go.drugbank.com/drugs/DB15354ApprovedInvestigationalrationale for the development of a therapy targeted against ANGPTL3. … Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein 3 (ANGPTL3) and the first drug of its kind.
Infliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalInfliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. … Inflectra, a first biosimilar drug product, was approved in 2016. In December 2017, Ixifi, a second biosimilar that was developed by Pfizer, was granted approval by the FDA.
Exemestane
go.drugbank.com/drugs/DB00990ApprovedInvestigationalExemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the ...
Products: EXEMESTAN AL 25 MG, EXEMESTAN 1A PHARMA 25MGQuinidine
go.drugbank.com/drugs/DB00908ApprovedQuinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species. … [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over the next few decades.
Categories: Antiarrhythmics, Class Ia, P-glycoprotein substrates with a Narrow Therapeutic IndexClogestone
go.drugbank.com/drugs/DB19526ExperimentalClogestone is a small molecule drug. Clogestone has a monoisotopic molecular weight of 364.18 Da.
Volpristin
go.drugbank.com/drugs/DB19604ExperimentalVolpristin is a small molecule drug. Volpristin has a monoisotopic molecular weight of 527.26 Da.
Categories: Streptogramin Group ASpirogermanium
go.drugbank.com/drugs/DB19618ExperimentalSpirogermanium is a small molecule drug. Spirogermanium has a monoisotopic molecular weight of 342.21 Da.