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Isavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalIt is approved by the FDA and EMA for the treatment of invasive aspergillosis and mucormycosis. It works by inhibiting fungal cell membrane synthesis. … It is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026].
Categories: Isavuconazole and Prodrugs, Triazole and tetrazole derivativesDaridorexant
go.drugbank.com/drugs/DB15031ApprovedInvestigationalInsomnia is characterized by difficulties with sleep onset and/or sleep maintenance and impairment of daytime functioning. … [A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin receptor antagonist approved in the market,[L41725] and by Health Canada on April 26, 2023.
Categories: Hypnotics and SedativesTisagenlecleucel
go.drugbank.com/drugs/DB13881ApprovedInvestigationalTisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual patient and genetically engineered to express a specific protein called a chimeric … It was granted approval by FDA in August 2017 under the market name Kymriah.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic cell and gene therapyVamorolone
go.drugbank.com/drugs/DB15114ApprovedInvestigationaland the most common form of muscular dystrophy in the United States. … Vamorolone is a novel and fully synthetic glucocorticoid developed by Santhera Pharmaceuticals.
Categories: Sex Hormones and InsulinsIpratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigational[A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved in 1986, while the combination product of ipratropium and [albuterol … Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent.
Mixtures: VENTOPIUM PLUS 0.5MG + 2.5MG/2.5ML NEBÜLIZASYON IÇIN INHALASYON ÇÖZELTISI ,20 FLAKON, Ipratropium Bromide and Albuterol SulfateCategories: fenoterol and ipratropium bromide, salbutamol and ipratropium bromideTrofinetide
go.drugbank.com/drugs/DB06045Approved[A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. … [L64112] The European Commission granted marketing authorization on August 24, 2026 for the treatment of neurobehavioral symptoms of Rett syndrome in adults and pediatric patients aged 5 years and older
Categories: Amino Acids, Peptides, and ProteinsHepatitis A Vaccine
go.drugbank.com/drugs/DB10989ApprovedInvestigational[A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely confers strong protection … [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]
Products: AVAXIM 80 U PEDIATRIC, VAQTA VACCINE 25 u/0.5 mlLysine
go.drugbank.com/drugs/DB00123ApprovedInvestigationalNutraceuticalCollagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. … Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it.
Mixtures: Aminosyn II and Dextrose, Aminosyn II and DextroseCategories: arginine and lysine, Blood and Blood Forming OrgansAchalasia
go.drugbank.com/conditions/DBCOND0032922Drugs: NifedipineSynonyms: Achalasia and cardiospasm