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Displaying results 2251 - 2260 of 2454 in total
  1. Drug

    Telmapitant

    go.drugbank.com/drugs/DB20768
    Experimental

    The usage of the INN stem '-pitant' in the name indicates that Telmapitant is a neurokinin NK1​ (substance P) receptor antagonist. Telmapitant has a monoisotopic molecular weight of 515.16 Da.

  2. Drug

    Metacetamol

    go.drugbank.com/drugs/DB21287
    Experimental

    Metacetamol is a small molecule drug. Metacetamol has a monoisotopic molecular weight of 151.06 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Inhibitors
  3. Drug

    Fluroxene

    go.drugbank.com/drugs/DB20681
    Experimental

    Fluroxene is a small molecule drug. Fluroxene has a monoisotopic molecular weight of 126.03 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  4. Drug

    Lapisteride

    go.drugbank.com/drugs/DB21206
    Experimental

    Lapisteride is a small molecule drug. The usage of the INN stem '-steride' in the name indicates that Lapisteride is a androgen/anabolic steroid. Lapisteride has a monoisotopic molecular weight of 464.3 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  5. Drug

    Pyridostigmine

    go.drugbank.com/drugs/DB00545
    ApprovedInvestigational

    Possible dose forms have been expanded to include extended-release tablets, syrups, and injections, marketed under various brand and generic names.[L32408, L32413]

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  6. Drug

    Adinazolam

    go.drugbank.com/drugs/DB00546
    Experimental

    Adinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant properties. Adinazolam was first developed to enhance the antidepressant effects of alprazolam. It has never been approved...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Zafirlukast

    go.drugbank.com/drugs/DB00549
    Approved

    Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed ...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  8. Drug

    Hydroxyzine

    go.drugbank.com/drugs/DB00557
    ApprovedInvestigational

    Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. It was first developed in 1955, and has since remained a rela...

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  9. Drug

    Cephalexin

    go.drugbank.com/drugs/DB00567
    ApprovedInvestigationalVet approved

    Cephalexin is the first of the first generation cephalosporins. This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthe...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates