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Methylprednisolone hemisuccinate
go.drugbank.com/drugs/DB14644ApprovedInvestigationalA water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Categories: Hormones, Hormone Substitutes, and Hormone Antagonists, Cytochrome P-450 CYP3A InducersProducts: Metasol 16 mg Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung, Metasol 32 mg Pulver und Lösungsmittel zur Herstellung einer Injektions-/InfusionslösungNifedipine
go.drugbank.com/drugs/DB01115ApprovedInvestigationalNifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine]. … [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer durations of action.
Synonyms: 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylesterMixtures: NIF TEN 50, Seaford Nifedipine and Lidocaine Hydrochloride CreamIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.
Synonyms: (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid, (±)-2-(p-isobutylphenyl)propionic acidInternational brands: Act-3, Alges-XKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigational[L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511] … Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.
Mixtures: Ixoba M, Acunivive 90Categories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDSRanitidine
go.drugbank.com/drugs/DB00863ApprovedWithdrawn[L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. … Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine].
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: RANOBEL 50 MG/2 ML ENJEKTABL AMPUL, 5 ADET, ULCURAN 50 MG 10 AMPULTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalIt possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent. … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding.
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsSynonyms: trans-4-aminomethylcyclohexane-1-carboxylic acid, trans-4-(Aminomethyl)cyclohexanecarboxylic acidClindamycin
go.drugbank.com/drugs/DB01190ApprovedInvestigationalVet approved[L11593] It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. … [A190657] Clindamycin is derived from, and has largely replaced, [lincomycin], a naturally occurring lincosamide and the eponymous member of this antibiotic class, due to its improved properties over
Synonyms: Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside, 7(S)-Chloro-7-deoxylincomycinInternational brands: Dalacin C, Dalacin T Topical SolutionDoxepin
go.drugbank.com/drugs/DB01142ApprovedInvestigational[T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. … Doxepin is a psychotropic agent with antidepressant and anxiolytic properties.
Categories: Adrenergic alpha-1 Receptor Antagonists, Heterocyclic Compounds, 1-RingProducts: Rho-doxepin-10 Mg Cap, APO-DOXEPIN CAPSULE 10 mgPentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigationalPentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties. … [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines
Mixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Categories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 SubstratesBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such … as [Carvedilol] and [Labetalol].
Synonyms: (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol, (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanolMixtures: CONCOR ® AM 5 MG / 10 MG, CONCOR ® AM 5 MG / 10 MG