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Displaying results 2251 - 2260 of 10000 in total
  1. Drug

    AAG-1

    go.drugbank.com/drugs/DB17199
    Experimental

    Synonyms: Furo(2,3-d)pyrimidin-4-amine, n-(4-methoxyphenyl)-n,2,6-trimethyl-, N-(4-methoxyphenyl)-n,2,6-trimethylfuro(2,3-d) pyrimidin-4-amine
  2. Drug

    Meropenem

    go.drugbank.com/drugs/DB00760
    ApprovedInvestigational

    In August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI). … Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  3. Drug

    Bacampicillin

    go.drugbank.com/drugs/DB01602
    ApprovedWithdrawn

    It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides. … Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration.

    Categories: Penicillin G, Heterocyclic Compounds, 2-RingSynonyms: 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, 1'-ethoxycarbonyloxyethyl-(6-D-α-aminophenylacetamido)penicillanate
  4. Drug

    Tabirafusp tedromer

    go.drugbank.com/drugs/DB19340
    Investigational

    Tabirafusp tedromer is under investigation in clinical trial NCT06556368 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants

    Synonyms: 3,5,8-Trioxa-4-phosphaundec-10-en-1-aminium,4-hydroxy-N,N,N,10-tetramethyl-9-oxo-, inner salt, 4-oxide, homopolymer,9-arm star compd. with 1,1'-[2-[11,11-bis[15-bromo-11,11-bis[(2-bromo-2-methyl-1-oxopropoxy, 1-[1,1,1-tris({3-[2-(2,2,2-tris{[(2-{α-(bromo / ethoxy / hydro / hydroxy)poly[1-(10,10-dimethyl-6-oxido-6-oxo-2,5,7-trioxa-10-aza-6λ5-phosphaundecan-10-ium-1-oyl)-1-methylethane-1,2-diyl]-ω-yl}-2-methylpropanoyl
  5. Drug

    AZD-2836

    go.drugbank.com/drugs/DB06031
    Investigational

    AZD-2836 is an inhibitor of the nonstructural protein 5A (NS5A).[A264853] The drug is being investigated for treatment of hepatitis C because AZD-2836 has in vitro anti-HCV activity.[A264858]

    Synonyms: 6-(3,4-Dimethoxyphenyl)-N-[4-(1H-1,2,4-triazol-1-yl)phenyl]-4-quinazolinamine
  6. Drug

    Suratadenoturev

    go.drugbank.com/drugs/DB18672
    Investigational

    Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.

    Synonyms: A recombinant replication-competent adenovirus type 5 (Ad-5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and replaced by an expression cassette containing, A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human telomerase reverse transcriptase (hTERT) and IRES, respectively.
  7. Drug

    Linifanib

    go.drugbank.com/drugs/DB06080
    Investigational

    Linifanib (ABT-869) is a small molecule vascular endothelial growth factor (VEGF) receptor-based kinase inhibitor that is designed to suppress tumor growth by preventing the formation of new blood vessels

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: UREA, N-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-N'-(2-FLUORO-5-METHYLPHENYL)-, N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N1-(2-fluoro-5-methylphenyl) urea
  8. Drug

    BG-P400-TAT

    go.drugbank.com/drugs/DB17104
    Experimental

    Synonyms: [4-(4-{1-[2-(2-{2-[2-(2-{2-[2-(4-guanidinomethyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethyl]-1H-[1,2,3]triazol-4-ylmethoxy}-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-acetic acid, 2-[4-[4-[[1-[2-[2-[2-[2-[2-[2-[2-[4-[(Diaminomethylideneamino)methyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]-3,5-diiodophenoxy]-3,5-diiodophenyl]acetic acid
  9. Drug

    Fosbretabulin

    go.drugbank.com/drugs/DB12577
    Investigational

    Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.

    Synonyms: Combretastatin A-4 phosphate, Combretastatin A4 phosphate
  10. Drug

    Pimasertib

    go.drugbank.com/drugs/DB14904
    Investigational

    Pimasertib is under investigation in clinical trial NCT01378377 (Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide