Tabirafusp tedromer
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Tabirafusp tedromer
- DrugBank Accession Number
- DB19340
- Background
Tabirafusp tedromer is under investigation in clinical trial NCT06556368 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (Wamd) - DAYBREAK).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 5418.851
Monoisotopic: 5407.334403 - Chemical Formula
- C194H348Br9N18O93P9
- Synonyms
- 1-[1,1,1-tris({3-[2-(2,2,2-tris{[(2-{α-(bromo / ethoxy / hydro / hydroxy)poly[1-(10,10-dimethyl-6-oxido-6-oxo-2,5,7-trioxa-10-aza-6λ5-phosphaundecan-10-ium-1-oyl)-1-methylethane-1,2-diyl]-ω-yl}-2-methylpropanoyl)oxy]methyl}ethoxy)acetamido]propanamido
- 3,5,8-Trioxa-4-phosphaundec-10-en-1-aminium,4-hydroxy-N,N,N,10-tetramethyl-9-oxo-, inner salt, 4-oxide, homopolymer,9-arm star compd. with 1,1'-[2-[11,11-bis[15-bromo-11,11-bis[(2-bromo-2-methyl-1-oxopropoxy)methyl]-15-methyl-3,7,14-trioxo-9,13-dioxa-2,6
- Tedromer
- External IDs
- OG-1802
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 8ES4CE6CXN
- CAS number
- 2412170-98-8
- InChI Key
- GRHIAJGAQUTOSV-UHFFFAOYSA-N
- InChI
- InChI=1S/C194H348Br9N18O93P9/c1-173(2,122-182(19,195)163(240)278-101-110-305-315(250,251)296-80-68-213(28,29)30)155(232)287-137-192(138-288-156(233)174(3,4)123-183(20,196)164(241)279-102-111-306-316(252,253)297-81-69-214(31,32)33,139-289-157(234)175(5,6)124-184(21,197)165(242)280-103-112-307-317(254,255)298-82-70-215(34,35)36)135-276-119-150(227)204-62-57-145(222)209-131-191(134-275-100-99-274-98-97-273-94-91-270-79-66-208-149(226)61-77-268-89-92-271-95-96-272-93-90-269-78-65-207-148(225)60-67-212-153(230)55-56-154(212)231,133-211-147(224)59-64-206-152(229)121-295-194(172(249)314-181(17,18)130-190(27,203)171(248)286-109-118-313-323(266,267)304-88-76-221(52,53)54,143-293-161(238)179(13,14)128-188(25,201)169(246)284-107-116-311-321(262,263)302-86-74-219(46,47)48)144-294-162(239)180(15,16)129-189(26,202)170(247)285-108-117-312-322(264,265)303-87-75-220(49,50)51)132-210-146(223)58-63-205-151(228)120-277-136-193(140-290-158(235)176(7,8)125-185(22,198)166(243)281-104-113-308-318(256,257)299-83-71-216(37,38)39,141-291-159(236)177(9,10)126-186(23,199)167(244)282-105-114-309-319(258,259)300-84-72-217(40,41)42)142-292-160(237)178(11,12)127-187(24,200)168(245)283-106-115-310-320(260,261)301-85-73-218(43,44)45/h55-56H,57-144H2,1-54H3,(H8-9,204,205,206,207,208,209,210,211,222,223,224,225,226,227,228,229,250,251,252,253,254,255,256,257,258,259,260,261,262,263,264,265,266,267)
- IUPAC Name
- SMILES
- CC(C)(CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)OC(=O)C(COC(=O)C(C)(C)CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)(COC(=O)C(C)(C)CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)OCC(=O)NCCC(=O)NCC(CNC(=O)CCNC(=O)COCC(COC(=O)C(C)(C)CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)(COC(=O)C(C)(C)CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)COC(=O)C(C)(C)CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)(CNC(=O)CCNC(=O)COCC(COC(=O)C(C)(C)CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)(COC(=O)C(C)(C)CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)COC(=O)C(C)(C)CC(C)(Br)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C)COCCOCCOCCOCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at August 22, 2024 14:02 / Updated at September 20, 2024 04:30