Search

Displaying results 2261 - 2270 of 10000 in total
  1. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    [L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I. … This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl, )ethyl)piperidine-1-carboxylate
  2. Drug

    Elzasonan

    go.drugbank.com/drugs/DB18969
    Investigational

    Elzasonan is under investigation in clinical trial NCT00275197 (A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSynonyms: (2z)-4-(3,4-dichlorphenyl)-2-(2-(4-methylpiperazin-1-yl)benzylidene)thiomorpholin-3-one, 3-thiomorpholinone, 4-(3,4-dichlorphenyl)-2-((2-(4-methyl-1-piperazinyl) phenyl)methylene)-, (2z)-
  3. Drug

    Mesosulfuron-methyl

    go.drugbank.com/drugs/DB15184
    Experimental

    Mesosulfuron-methyl is under investigation in clinical trial NCT01118117 (A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery).

    Synonyms: METHYL 2-(3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)UREIDOSULFONYL)-4-METHANESULFONAMIDOMETHYLBENZOATE, 2-(((((4,6-DIMETHOXY-2-PYRIMIDINYL)AMINO)CARBONYL)AMINO)SULFONYL)-4-(((METHYLSULFONYL)AMINO)METHYL)BENZOIC ACID METHYL ESTER
  4. Drug

    D-arginine

    go.drugbank.com/drugs/DB04027
    Experimental

    A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).

    Synonyms: (2R)-2-amino-5-guanidinopentanoic acid, D-2-Amino-5-guanidinovaleric acid
  5. Drug

    Cobalt chloride

    go.drugbank.com/drugs/DB14206
    Approved

    Synonyms: cobalt(2+) chlorideCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  6. Drug

    Thiosalicylic acid

    go.drugbank.com/drugs/DB14026
    Experimental

    Synonyms: 2-Carboxythiophenol, 2-Thiosalicylic acid
  7. Drug

    Fenbendazole

    go.drugbank.com/drugs/DB11410
    InvestigationalVet approved

    Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. … It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: methyl 5-(phenylthio)-2-benzimidazolecarbamate, 2-(methoxycarbonylamino)-5-(phenylthio)benzimidazole
  8. Drug

    Uracil C-13

    go.drugbank.com/drugs/DB16345
    Investigational

    Uracil C-13 is under investigation in clinical trial NCT01677338 (Phase 2 Study to Evaluate the Preliminary Performance of the C13-URA Breath Test Kit in Dyspeptic Subjects).

    Synonyms: Uracil C-13, 2-, Uracil (2-13c)
  9. Drug

    (2S)-({(5Z)-5-[(5-Ethyl-2-furyl)methylene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl}amino)(4-fluorophenyl)acetic acid

    go.drugbank.com/drugs/DB08706
    Experimental

    Synonyms: (2S)-({(5Z)-5-[(5-Ethyl-2-furyl)methylene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl}amino)(4-fluorophenyl)acetic acid
  10. Drug

    3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione

    go.drugbank.com/drugs/DB07458
    Experimental

    Synonyms: 3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione