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Displaying results 2261 - 2270 of 10000 in total
  1. Drug

    Niraparib

    go.drugbank.com/drugs/DB11793
    ApprovedInvestigational

    Niraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. … [L43747] On December 12, 2025, the FDA expanded niraparib and abiraterone acetate (AKEEGA) with prednisone for the treatment of patients with BRCA2-mutated metastatic castration-sensitive prostate cancer

    Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic Index
  2. Drug

    Phthalylsulfathiazole

    go.drugbank.com/drugs/DB13248
    Approved

    Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006].

    Categories: combinations of sulfonamides
  3. Drug

    Nafamostat

    go.drugbank.com/drugs/DB12598
    Investigational

    The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing continuous renal replacement therapy due to acute kidney injury. … Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties.

  4. Drug

    Flavoxate

    go.drugbank.com/drugs/DB01148
    Approved

    A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. … It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]

  5. Drug

    Pleospora herbarum

    go.drugbank.com/drugs/DB10825
    Approved

    Pleospora herbarum is a fungus which can provoke allergic reactions. Pleospora herbarum extract is used in allergenic testing.

    Mixtures: Treatment Set TS128871, Treatment Set TS129085
  6. Drug

    Sporisorium cruentum

    go.drugbank.com/drugs/DB10873
    Approved

    Sporisorium cruentum is a fungus which can provoke allergic reactions. Sporisorium cruentum extract is used in allergenic testing.

    Mixtures: Treatment Set TS128871, Treatment Set TS329906
  7. Drug

    Dexibuprofen

    go.drugbank.com/drugs/DB09213
    ApprovedWithdrawn

    Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. … It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer.

    Mixtures: SUITROM CAF TABLETA RECUBIERTAProducts: IBUDEX 400 FILM TABLET, 10 ADET, IBUDEX 400 FILM TABLET, 30 ADET
  8. Drug

    Ustilago avenae

    go.drugbank.com/drugs/DB10704
    Approved

    Ustilago avenae is a fungus which can provoke allergic reactions. Ustilago avenae extract is used in allergenic testing.

    Mixtures: Treatment Set TS329906, Treatment Set TS330370
  9. Drug

    Thiohexam

    go.drugbank.com/drugs/DB14200
    Approved

    Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.

  10. Drug

    Diethylcarbamazine

    go.drugbank.com/drugs/DB00711
    ApprovedInvestigationalVet approvedWithdrawn

    An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.